SCHEMBL4363906

SCHEMBL4363906

COC(=O)c1cc(Cl)ccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.62
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
LMNA P02545 3/20 0.60
MAPT P10636 2/20 0.60
HTT P42858 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
ALDH1A1 P00352 5/20 0.59
TP53 P04637 1/20 0.59
SMN1; SMN2 Q16637 3/20 0.55
SLC6A4 P31645 1/20 0.54
SLC6A3 Q01959 1/20 0.54
NR4A2 P43354 2/20 0.54
TSHR P16473 1/20 0.53
ERCC5 P28715 1/20 0.51
FEN1 P39748 1/20 0.51
KDM4E B2RXH2 1/20 0.49
ALPL P05186 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11300844 0.98 ABL1 (0.61) ABL1MEN1KMT2ALMNAMAPT
SCHEMBL6100118 0.86 ABL1 (0.70) ABL1MEN1KMT2ALMNAMAPT
SCHEMBL608814 0.84 ABL1 (0.68) ABL1MEN1KMT2AMAPTALDH1A1
SCHEMBL11096701 0.83 ALDH1A1 (0.63) ABL1MEN1KMT2ALMNAMAPT
SCHEMBL2121550 0.83 ALDH1A1 (0.63) ABL1MEN1KMT2ALMNAMAPT
SCHEMBL4308995 0.82 ABL1 (0.61) ABL1MEN1KMT2ALMNAMAPT
SCHEMBL123068 0.82 CA1 (0.67) ABL1MEN1KMT2ALMNAMAPT
SCHEMBL1462096 0.82 ABL1 (0.61) ABL1MEN1KMT2ALMNAMAPT
SCHEMBL29406512 0.82 ABL1 (0.61) ABL1MEN1KMT2ALMNAMAPT
SCHEMBL2452734 0.82 ABL1 (0.61) ABL1MEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4331364-A2 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO Corteva Agriscience LLC (US) 2024-03-06 EP claimed
CN-113387790-B Preparation method of chloroalkoxy-1, 3-diphenyl-beta-diketone 佛山华铕光电材料股份有限公司 2022-08-05 CN claimed
CN-113387790-A Preparation method of chloroalkoxy-1, 3-diphenyl-beta-diketone 佛山华铕光电材料股份有限公司 2021-09-14 CN claimed
US-10736316-B2 Silica particles functionalized and loaded with fungicidal agents, their manufacture and their use as systems of targeted and controlled release of fungicides PRODUCTOS CITROSOL, S.A. (ES) 2020-08-11 US claimed
US-20180368396-A1 SILICA PARTICLES FUNCTIONALIZED AND LOADED WITH FUNGICIDAL AGENTS, THEIR MANUFACTURE AND THEIR USE AS SYSTEMS OF TARGETED AND CONTROLLED RELEASE OF FUNGICIDES PRODUCTOS CITROSOL, S.A. (ES) 2018-12-27 US claimed
EP-3403503-A1 SILICA PARTICLES FUNCTIONALIZED AND LOADED WITH FUNGICIDAL AGENTS, THEIR MANUFACTURE AND THEIR USE AS SYSTEMS OF TARGETED AND CONTROLLED RELEASE OF FUNGICIDES Productos Citrosol, S.A. (ES) 2018-11-21 EP claimed
US-20140194288-A1 PLANT SUPPORT FORMULATION, VEHICLE FOR THE DELIVERY AND TRANSLOCATION OF PHYTOLOGICALLY BENEFICIAL SUBSTANCES AND COMPOSITIONS CONTAINING SAME NORTH-WEST UNIVERSITY (ZA) 2014-07-10 US claimed
US-20120302442-A1 PLANT SUPPORT FORMULATION, VEHICLE FOR THE DELIVERY AND TRANSLOCATION OF PHYTOLOGICALLY BENEFICIAL SUBSTANCES AND COMPOSITIONS CONTAINING SAME NORTH-WEST UNIVERSITY (ZA) 2012-11-29 US claimed
US-20090192040-A1 PLANT SUPPORT FORMULATION, VEHICLE FOR THE DELIVERY AND TRANSLOCATION OF PHYTOLOGICALLY BENEFICAL SUBSTANCES AND COMPOSITIONS CONTAINING SAME NORTH-WEST UNIVERSITY (ZA) 2009-07-30 US claimed
EP-1988774-A2 COMPOSITION IN THE FORM OF A MICROEMULSION CONTAINING FREE FATTY ACIDS AND/OR FREE FATTY ACID DERIVATIVES North-West University (ZA) 2008-11-12 EP claimed
WO-2007096833-A2 COMPOSITION IN THE FORM OF A MICROEMULSION CONTAINING FREE FATTY ACIDS AND/OR FREE FATTY ACID DERIVATIVES NORTH-WEST UNIVERSITY (ZA) 2007-08-30 WO claimed
US-20030092634-A1 Novel compounds and compositions as protease inhibitors AXYS PHARMACEUTICALS, INC. 2003-05-15 US claimed
US-6506733-B1 Which process comprises hydrogenating a compound of Formula 9: presence of a catalytic amount of 20% palladium hydroxide on carbon. AXYS PHARMACEUTICALS, INC. 2003-01-14 US claimed
EP-1159260-A1 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2001-12-05 EP claimed
WO-2000055124-A2 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2000-09-21 WO claimed
US-4341899-A OF METHYL-2,5-DICHLOROBENZOATE WITH HYDROGEN, NICKEL CATALYST RHONE-POULENC AGROCHIMIE (FR) 1982-07-27 US claimed
US-20250338846-A1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE, LLC (US) 2025-11-06 US disclosed
CN-119907626-A Compositions having pesticidal utility and methods related thereto 科迪华农业科技有限责任公司 2025-04-29 CN disclosed
US-4102924-A REACTING ACYLAMINO-ARYLS WITH HALO-ARYLS BAYER AKTIENGESELLSCHAFT (DE) 1978-07-25 US disclosed
US-3966728-A ANTIPEPTIC ULCER ACTIVITY NIPPON SHINYAKU CO., LTD. (JA) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250338846-A1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO ACHE, DDT, PLA2G2D ABL1 3182/4885MEN1 457/4885KMT2A 3583/4885
US-20180368396-A1 SILICA PARTICLES FUNCTIONALIZED AND LOADED WITH FUNGICIDAL AGENTS, THEIR MANUFACTURE AND THEIR USE AS SYSTEMS OF TARGETED AND CONTROLLED RELEASE OF FUNGICIDES ERG28, CYP51A1, MSR1 ABL1 2607/4885MEN1 881/4885KMT2A 3215/4885
US-10736316-B2 Silica particles functionalized and loaded with fungicidal agents, their manufacture and their use as systems of targeted and controlled release of fungicides ERG28, CYP51A1, MSR1 ABL1 2607/4885MEN1 881/4885KMT2A 3215/4885
US-20030092634-A1 Novel compounds and compositions as protease inhibitors SERPINB1, HPN, CTRL ABL1 995/4885MEN1 4105/4885KMT2A 4353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.