SCHEMBL430932

SCHEMBL430932

O=[PH](O)C(O)c1ccccc1.[NaH]

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
MAPK1 P28482 1/20 0.44
SRC P12931 2/20 0.41
CYP2D6 P10635 1/20 0.41
CES2 O00748 2/20 0.40
CES1 P23141 2/20 0.40
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9175682 1.00 LMNA (0.44) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL5173363 1.00 LMNA (0.44) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL10765606 0.98 LMNA (0.43) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL8601633 0.98 LMNA (0.43) LMNAMAPK1SRCCYP2D6CES2
Water SCHEMBL17513119 0.98 LMNA (0.43) LMNAMAPK1SRCCYP2D6CES2
Water SCHEMBL9138593 0.98 LMNA (0.43) LMNAMAPK1SRCCYP2D6CES2
Water SCHEMBL17513118 0.98 LMNA (0.43) LMNAMAPK1SRCCYP2D6CES2
Benzene SCHEMBL23120173 0.98 LMNA (0.46) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL9036 0.98 LMNA (0.46) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL21723253 0.98 LMNA (0.46) LMNAMAPK1SRCCYP2D6CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2415473-B1 ORAL CARE COMPOSITIONS CONTAINING COMBINATIONS OF ANTI-BACTERIAL AND HOST-RESPONSE MODULATING AGENTS PROCTER & GAMBLE (US) 2014-09-17 EP claimed
EP-0464059-A1 METHOD OF DE-INKING WASTE PAPER MATERIALS. BDL SPECIALIST PROD (GB) 1992-01-08 EP claimed
WO-1990010749-A1 METHOD OF DE-INKING WASTE PAPER MATERIALS BDL SPECIALIST PRODUCTS LIMITED (GB) 1990-09-20 WO claimed
EP-0219073-B1 STABILIZATION OF INTERFERONS F. HOFFMANN-LA ROCHE AG (CH) 1990-03-07 EP claimed
EP-0306546-A1 Irradiation produced AMPS/Am copolymers in thickened acid compositions PHILLIPS PETROLEUM COMPANY (US) 1989-03-15 EP claimed
EP-0264859-A2 2-(2-substituted benzoyl)-4-(substituted)-1,3-cyclohexanediones, a process for their production and a herbicidal composition containing them STAUFFER CHEMICAL COMPANY (US) 1988-04-27 EP claimed
EP-0264737-A2 2-(2-substituted benzoyl)-4-(substituted imino, oximino or carbonyl)-1,3-cyclo-hexanediones, a process for their production, and a herbicidal composition containing them STAUFFER CHEMICAL COMPANY (US) 1988-04-27 EP claimed
EP-0259285-A2 Process for improving the eating and preservation qualities of uncured pork products Geo. A. Hormel & Co. (US) 1988-03-09 EP claimed
EP-0249149-A1 Certain 3-benzoyl-4-oxolactams STAUFFER CHEMICAL COMPANY (US) 1987-12-16 EP claimed
EP-4189062-A1 INDUSTRIAL FERMENTATION PROCESS FOR BACILLUS USING FEED RATE SHIFT BASF SE (DE) 2023-06-07 EP disclosed
EP-4189104-A1 INDUSTRIAL FERMENTATION PROCESS FOR BACILLUS USING PARTIAL HARVEST BASF SE (DE) 2023-06-07 EP disclosed
EP-4189103-A1 INDUSTRIAL FERMENTATION PROCESS FOR BACILLUS USING TEMPERATURE SHIFT BASF SE (DE) 2023-06-07 EP disclosed
WO-2023097309-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VISCERAL PAIN IRONWOOD PHARMACEUTICALS, INC. (US) 2023-06-01 WO disclosed
US-11639937-B2 Fluorescent methods and materials for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2023-05-02 US disclosed
EP-0237150-A2 Improved radionuclide antibody coupling NEORX CORPORATION (US) 1987-09-16 EP disclosed
EP-0236059-A2 Preparation of erythropoietin-producing cells and production process of erythropoietin using same SNOW BRAND MILK PRODUCTS CO. LTD. (JP) 1987-09-09 EP disclosed
EP-0234599-A1 Cysteine-depleted muteins of interleukin-2, their preparation, formulations containing them, and genes, vectors and organisms suitable for use in the preparation of said muteins CETUS ONCOLOGY CORPORATION (US) 1987-09-02 EP disclosed
EP-0234938-A2 Application of tetrathiafulvalenes in bioelectrochemical processes CRANFIELD BIOTECHNOLOGY LTD (GB) 1987-09-02 EP disclosed
WO-1987004726-A1 PROCESS FOR PURIFYING RECOMBINANT PROTEINS, AND PRODUCTS THEREOF CAMBRIDGE BIOSCIENCE CORPORATION (US) 1987-08-13 WO disclosed
EP-0229016-A2 Interleukin-2 compositions SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1987-07-15 EP disclosed