SCHEMBL430933

SCHEMBL430933

CCC(=O)O[Si](OC(=O)CC)(OC(=O)CC)OC(=O)CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
NAAA Q02083 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
FFAR3 O14843 1/20 0.37
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
SOAT1 P35610 1/20 0.35
HIF1A Q16665 3/20 0.33
CYP1A2 P05177 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
WRN Q14191 1/20 0.33
ESR1 P03372 2/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17752981 0.89 ALDH1A1 (0.36) ALDH1A1NAAATDP1FFAR3TSHR
SCHEMBL21295312 0.89 ALDH1A1 (0.36) ALDH1A1NAAATDP1FFAR3TSHR
SCHEMBL5444970 0.86 ALDH1A1 (0.36) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL4347455 0.86 ALDH1A1 (0.36) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL7885707 0.86 ALDH1A1 (0.36) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL3912259 0.84 ALDH1A1 (0.35) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL7892098 0.84 ALDH1A1 (0.35) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL10777423 0.84 ALDH1A1 (0.35) ALDH1A1NAAATDP1FFAR3MGAM
Lithium SCHEMBL31471667 0.82 ALDH1A1 (0.33) ALDH1A1NAAAMGAMGAASI
Lithium SCHEMBL31471668 0.82 ALDH1A1 (0.33) ALDH1A1NAAAMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1530961-B1 Emulsion containing hollow organosilicon particles OREAL (FR) 2009-08-05 EP claimed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP claimed
WO-2024177097-A1 HYDROXYL GROUP-CONTAINING POLYAMIDE RESIN COMPOSITION, LAMINATE, PACKAGING MATERIAL, AND GAS BARRIER MATERIAL 東洋紡株式会社 2024-08-29 WO disclosed
WO-2024177099-A1 POLYESTER RESIN COMPOSITION, LAYERED PRODUCT, PACKAGING MATERIAL, AND GAS BARRIER MATERIAL 東洋紡株式会社 2024-08-29 WO disclosed
EP-3021948-B1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS OREAL (FR) 2019-08-21 EP disclosed
US-10316046-B2 Method for producing acyloxysilanes, acyloxysilanes obtained thereby, and use of same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-11 US disclosed
US-20180044359-A1 Method for Producing Acyloxysilanes, Acyloxysilanes Obtained Thereby, and Use of Same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2018-02-15 US disclosed
EP-2462197-B1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF ORÉAL L (FR) 2016-09-21 EP disclosed
WO-2016116492-A1 OIL/OIL EMULSION COMPRISING SOLID MICROPARTICLES, AT LEAST A FIRST OILY PHASE, AT LEAST A SECOND OILY PHASE AND AT LEAST A THIRD OILY PHASE THAT ARE MUTUALLY IMMISCIBLE L'OREAL (FR) 2016-07-28 WO disclosed
WO-2016116488-A1 OIL/OIL EMULSION COMPRISING SOLID MICROPARTICLES, AT LEAST ONE HYDROCARBON-BASED RESIN, AT LEAST A FIRST OILY PHASE AND AT LEAST A SECOND OILY PHASE L'OREAL (FR) 2016-07-28 WO disclosed
WO-2016116475-A1 O/O EMULSION CONTAINING MICROPARTICLES WITH A BREAK IN THE CURVATURED PART, COMPOSITIONS COMPRISING SAME AND USE OF MICROPARTICLES FOR STABILIZING THE O/O EMULSIONS L'OREAL (FR) 2016-07-28 WO disclosed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP disclosed
EP-1507829-A1 FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA Nippon Shokubai Co., Ltd. (JP) 2005-02-23 EP disclosed
WO-2003099934-A1 FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA NIPPON SHOKUBAI CO., LTD. (JP) 2003-12-04 WO disclosed
US-6297340-B1 WITHOUT ADDING ANY OXYGEN, AND TO REDUCE THE DANGER OF FIRE OREXPLOSION, REACTING AROMATIC VINYL COMPOUNDS OR ALLYL HALIDES WITH A SILICON COMPOUND HAVING HYDROSILYL GROUPS IN PRESENCE OF A CARBOXYLIC ACID, A SILYL ESTER OF A SULFONIC DOW CORNING ASIA, LTD. (JP) 2001-10-02 US disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-5130167-A For automobiles, vinyl polymers containing silicon groups, epoxy groups and hydroxy groups KANSAI PAINT COMPANY, LIMITED (JP) 1992-07-14 US disclosed
EP-0173278-B1 ROOM TEMPERATURE-CURABLE RESIN COMPOSITION DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-11-07 EP disclosed
US-4818790-A Room-temperature-curable resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0173278-A2 Room temperature-curable resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044359-A1 Method for Producing Acyloxysilanes, Acyloxysilanes Obtained Thereby, and Use of Same COASY, AGPS, CA7 ALDH1A1 176/4885NAAA 55/4885TDP1 4683/4885
US-10316046-B2 Method for producing acyloxysilanes, acyloxysilanes obtained thereby, and use of same COASY, AGPS, CA7 ALDH1A1 176/4885NAAA 55/4885TDP1 4683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.