Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311504 | 0.90 | TLR8 (0.34) | PDE4APDE4BPDE4CPDE4DTLR8 | |
| SCHEMBL4321907 | 0.89 | — | — | |
| SCHEMBL4329081 | 0.87 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4326967 | 0.87 | TLR8 (0.32) | TLR8 | |
| SCHEMBL4324672 | 0.85 | TLR8 (0.34) | TLR8 | |
| SCHEMBL5027823 | 0.82 | TLR7 (0.33) | TLR8 | |
| SCHEMBL1456920 | 0.81 | TLR8 (0.34) | TLR8 | |
| SCHEMBL13996156 | 0.81 | TLR8 (0.40) | TLR8 | |
| SCHEMBL4313948 | 0.81 | — | — | |
| SCHEMBL4321420 | 0.81 | HTT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735421-B2 | Imidazoquinolinyl sulfonamides | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20090062272-A1 | IMIDAZOQUINOLINYL SULFONAMIDES | 3M INNOVATIVE PROPERTIES COMPANY | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062272-A1 | IMIDAZOQUINOLINYL SULFONAMIDES | IL2, EIF2AK2, IFNG | PDE4A 2032/4885PDE4B 2885/4885PDE4C 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.