Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732725 | 0.88 | MAPT (0.61) | MAPTTDP1HTTALDH1A1MYC | |
| SCHEMBL2425023 | 0.85 | MAPT (0.68) | MAPTTDP1HTTALDH1A1MYC | |
| SCHEMBL5144939 | 0.85 | HTT (0.51) | MAPTTDP1HTTALDH1A1MAPK1 | |
| SCHEMBL30466426 | 0.85 | MAPT (0.68) | MAPTTDP1HTTALDH1A1MYC | |
| SCHEMBL102827 | 0.84 | MAPT (0.72) | MAPTTDP1HTTALDH1A1MYC | |
| SCHEMBL4446942 | 0.83 | TTR (0.51) | MAPTTDP1HTTALDH1A1CDC25B | |
| SCHEMBL28167808 | 0.83 | MAPT (0.49) | MAPTTDP1HTTALDH1A1MYC | |
| SCHEMBL16513023 | 0.83 | HTT (0.50) | MAPTTDP1HTTALDH1A1MYC | |
| Hydrochloric Acid SCHEMBL5061862 | 0.82 | MAPT (0.70) | MAPTTDP1HTTALDH1A1MYC | |
| Water SCHEMBL9749470 | 0.82 | MAPT (0.70) | MAPTTDP1HTTALDH1A1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069430-A1 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROPHARMA, S.A. (ES) | 2009-03-12 | — | — | US | disclosed |
| EP-1976823-A1 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Neuropharma, S.A. (ES) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007068754-A1 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROPHARMA, S.A. (ES) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069430-A1 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | CACNA1B, CACNB1, CACNA1C | MAPT 295/4885TDP1 1184/4885HTT 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.