Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309406 | 0.88 | MAPT (0.62) | MAPTTDP1ALDH1A1MYCCDC25B | |
| SCHEMBL30466426 | 0.88 | MAPT (0.68) | MAPTTDP1ALDH1A1MYCCDC25B | |
| SCHEMBL2425023 | 0.88 | MAPT (0.68) | MAPTTDP1ALDH1A1MYCCDC25B | |
| SCHEMBL11427275 | 0.85 | MAPT (0.48) | MAPTTDP1ALDH1A1CDC25BKDM4E | |
| SCHEMBL57368 | 0.84 | MAPT (0.62) | MAPTTDP1ALDH1A1MYCCDC25B | |
| SCHEMBL20187687 | 0.84 | MAPT (0.53) | MAPTTDP1ALDH1A1MYCCDC25B | |
| SCHEMBL4143348 | 0.84 | MAPT (0.68) | MAPTTDP1ALDH1A1MYCKDM4E | |
| SCHEMBL31335961 | 0.84 | MAPT (0.62) | MAPTTDP1ALDH1A1MYCCDC25B | |
| SCHEMBL27822908 | 0.84 | CA12 (0.57) | MAPTTDP1ALDH1A1MYCCDC25B | |
| SCHEMBL4779654 | 0.83 | LMNA (0.51) | MAPTTDP1ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| US-12486258-B2 | Compounds and methods for regulating insulin secretion | THE BROAD INSTITUTE, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |
| US-20230142508-A1 | COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION | THE BROAD INSTITUTE, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230142508-A1 | COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION | THE BROAD INSTITUTE, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230142508-A1 | COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION | THE BROAD INSTITUTE, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-11555031-B2 | Compounds and methods for regulating insulin secretion | THE BROAD INSTITUTE, INC. (US) | 2023-01-17 | — | — | US | disclosed |
| US-11203659-B2 | Method for producing polyurethane, epoxy carboxylate composition, polyurethane, and polyurethane resin composition | SHOWA DENKO K. K. (JP) | 2021-12-21 | — | — | US | disclosed |
| WO-2021224818-A1 | ISOINDOLONE COMPOUNDS AS HPK1 INHIBITORS | PFIZER INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| US-20210221938-A1 | METHOD FOR PRODUCING POLYURETHANE, EPOXY CARBOXYLATE COMPOSITION, POLYURETHANE, AND POLYURETHANE RESIN COMPOSITION | SHOWA DENKO K. K. (JP) | 2021-07-22 | — | — | US | disclosed |
| US-7601712-B2 | Such as (1)-2-(4-chloro-3-((2-chloro-4-(((2S)-4-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-ly)methoxy)benzoyl)amino)phenyl)-2-methylpropanoic acid; prostaglandin receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| WO-2009103484-A1 | SGK1 INHIBITORS FOR THE PROPHYLAXIS AND/OR THERAPY OF VIRAL DISEASES AND/OR CARCINOMAS | MERCK PATENT GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1666473-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1317241-A2 | SHAMPOO COMPOSITIONS WITH CATIONIC POLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002022091-A2 | SHAMPOO COMPOSITIONS WITH CATIONIC POLYMERS | PROCTER & GAMBLE COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
| US-20020012646-A1 | Shampoo compositions with cationic polymers | PROCTER & GAMBLE COMPANY, THE | 2002-01-31 | — | — | US | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142508-A1 | COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION | IAPP, GPR119, PNLIP | MAPT 4653/4885TDP1 4637/4885ALDH1A1 4536/4885 |
| US-11555031-B2 | Compounds and methods for regulating insulin secretion | IAPP, GPR119, INSR | MAPT 4534/4885TDP1 4702/4885ALDH1A1 3610/4885 |
| US-12486258-B2 | Compounds and methods for regulating insulin secretion | IAPP, GPR119, PNLIP | MAPT 4653/4885TDP1 4637/4885ALDH1A1 4536/4885 |
| US-20020012646-A1 | Shampoo compositions with cationic polymers | S100P, PSAP, PHOSPHO1 | MAPT 3455/4885TDP1 4201/4885ALDH1A1 4384/4885 |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | GPR17, CYSLTR1, KIT | MAPT 1750/4885TDP1 4293/4885ALDH1A1 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.