Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.59 |
| ▸ | EP300 | Q09472 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4315290 | 0.91 | CREBBP (0.58) | CREBBPEP300KMT2AMEN1ICAM1 | |
| SCHEMBL3645168 | 0.91 | CREBBP (0.52) | CREBBPEP300KMT2AMEN1ICAM1 | |
| SCHEMBL4505041 | 0.88 | MEN1 (0.54) | CREBBPEP300KMT2AMEN1ALDH1A1 | |
| SCHEMBL4311189 | 0.86 | CREBBP (0.49) | CREBBPEP300KMT2AMEN1ICAM1 | |
| SCHEMBL3811958 | 0.86 | KMT2A (0.64) | CREBBPEP300KMT2AMEN1ICAM1 | |
| SCHEMBL4312331 | 0.83 | CREBBP (0.52) | CREBBPEP300KMT2AMEN1ALDH1A1 | |
| SCHEMBL4321064 | 0.83 | CREBBP (0.46) | CREBBPEP300KMT2AMEN1ICAM1 | |
| SCHEMBL4308378 | 0.82 | CREBBP (0.49) | CREBBPEP300KMT2AMEN1ICAM1 | |
| SCHEMBL4721279 | 0.80 | CREBBP (0.52) | CREBBPEP300KMT2AMEN1ICAM1 | |
| SCHEMBL14281436 | 0.80 | KMT2A (0.67) | CREBBPEP300KMT2AMEN1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |