Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311026 | 0.88 | CREBBP (0.47) | CREBBPRAB9ATP53NPC1HPGD | |
| SCHEMBL4308378 | 0.84 | CREBBP (0.49) | CREBBPRAB9ANPC1HPGDEP300 | |
| SCHEMBL4315290 | 0.83 | CREBBP (0.58) | CREBBPRAB9ACYP2C9NPC1HPGD | |
| SCHEMBL4309447 | 0.83 | CREBBP (0.59) | CREBBPEP300KMT2AALDH1A1MEN1 | |
| SCHEMBL4321064 | 0.82 | CREBBP (0.46) | CREBBPRAB9ANPC1EP300KMT2A | |
| SCHEMBL4721279 | 0.80 | CREBBP (0.52) | CREBBPRAB9ACYP2C9CYP2C19NPC1 | |
| SCHEMBL3640912 | 0.80 | ALDH1A1 (0.46) | CREBBPRAB9ANPC1HPGDEP300 | |
| SCHEMBL10235987 | 0.80 | ALDH1A1 (0.49) | CREBBPRAB9ANPC1HPGDEP300 | |
| SCHEMBL2249806 | 0.80 | CREBBP (0.40) | CREBBPRAB9ATP53CYP2C9CYP2C19 | |
| SCHEMBL2526406 | 0.80 | CREBBP (0.48) | CREBBPRAB9ACYP2C9NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |