Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31024252 | 0.81 | PIN1 (0.53) | SCN10AKIF11 | |
| SCHEMBL4305878 | 0.81 | EGLN1 (0.81) | EGLN1HRH4HRH3KDM4C | |
| SCHEMBL4564769 | 0.81 | EGLN1 (0.64) | EGLN1HRH4HRH3CNR2HDAC3 | |
| SCHEMBL13625961 | 0.80 | EGLN1 (0.82) | EGLN1 | |
| SCHEMBL4302354 | 0.77 | EGLN1 (0.56) | EGLN1 | |
| SCHEMBL31024256 | 0.77 | SCN10A (0.41) | HRH4SCN10AHDAC6KIF11 | |
| SCHEMBL4307360 | 0.77 | EGLN1 (0.67) | EGLN1CNR2HDAC3HDAC1HDAC2 | |
| SCHEMBL17154106 | 0.76 | EGLN1 (0.55) | EGLN1CNR2 | |
| SCHEMBL4303435 | 0.76 | EGLN1 (0.65) | EGLN1HRH4HRH3CNR2EGLN3 | |
| SCHEMBL4313112 | 0.76 | EGLN1 (0.57) | EGLN1KDM4CEGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134754-A1 | BENZOIMIDAZOLE GLYCINAMIDES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-05 | — | — | WO | disclosed |
| WO-2009134754-A1 | BENZOIMIDAZOLE GLYCINAMIDES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-05 | — | — | WO | disclosed |