Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.68 |
| ▸ | IDO1 | P14902 | 1/20 | 0.68 |
| ▸ | CDK2 | P24941 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indazole SCHEMBL1221882 | 0.82 | HSP90AA1 (1.00) | HSP90AA1IDO1CDK2ABCB1DYRK1A | |
| Indazole SCHEMBL29355507 | 0.82 | — | — | |
| Indazole SCHEMBL6295 | 0.82 | — | — | |
| Indazole SCHEMBL5221603 | 0.80 | HSP90AA1 (0.95) | HSP90AA1IDO1CDK2ABCB1DYRK1A | |
| Indazole SCHEMBL21058156 | 0.80 | HSP90AA1 (0.95) | HSP90AA1IDO1CDK2ABCB1DYRK1A | |
| Indazole SCHEMBL9407408 | 0.80 | HSP90AA1 (0.95) | HSP90AA1IDO1CDK2ABCB1DYRK1A | |
| Indazole SCHEMBL5420749 | 0.80 | HSP90AA1 (0.95) | HSP90AA1IDO1CDK2ABCB1DYRK1A | |
| Indazole SCHEMBL7371212 | 0.80 | HSP90AA1 (0.95) | HSP90AA1IDO1CDK2ABCB1DYRK1A | |
| Indazole SCHEMBL3540508 | 0.80 | HSP90AA1 (0.95) | HSP90AA1IDO1CDK2ABCB1DYRK1A | |
| Indazole SCHEMBL110751 | 0.80 | HSP90AA1 (0.95) | HSP90AA1IDO1CDK2ABCB1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209552-A1 | Organic Compounds | NOVARTIS AG | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209552-A1 | Organic Compounds | SLCO1B3, SLCO1B1, SLC10A6 | HSP90AA1 4733/4885IDO1 2561/4885CDK2 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.