Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.59 |
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.50 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | S100B | P04271 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235372 | 0.79 | PRSS1 (0.61) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL12348104 | 0.75 | PRSS1 (0.52) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL25808192 | 0.75 | PRSS1 (0.56) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL429697 | 0.75 | ST14 (0.59) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL428950 | 0.75 | PRSS1 (1.00) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL15145313 | 0.74 | PRSS1 (0.50) | PRSS1PRSS2PRSS3F2ST14 | |
| Hydrochloric Acid SCHEMBL11613449 | 0.73 | PRSS1 (0.96) | PRSS1PRSS2PRSS3F2ST14 | |
| Hydrochloric Acid SCHEMBL1550092 | 0.73 | ST14 (0.57) | PRSS1PRSS2PRSS3F2ST14 | |
| Hydrochloric Acid SCHEMBL25262157 | 0.72 | ST14 (0.55) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL9650651 | 0.72 | PRSS1 (0.81) | PRSS1PRSS2PRSS3F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681504-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | Icagen, Inc. (US) | 2020-07-22 | — | — | EP | disclosed |
| WO-2019055754-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN, INC. (US) | 2019-03-21 | — | — | WO | disclosed |
| EP-2084519-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | Los Alamos National Security, LLC (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008127291-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-10-23 | — | — | WO | disclosed |