Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431983 | 0.86 | NPSR1 (0.50) | HSP90AA1NPSR1TOP1USP2MAPT | |
| SCHEMBL11072301 | 0.84 | NPSR1 (0.49) | HSP90AA1NPSR1TOP1USP2MAPT | |
| Bromide SCHEMBL431069 | 0.84 | NPSR1 (0.49) | HSP90AA1NPSR1TOP1USP2MAPT | |
| SCHEMBL11072297 | 0.81 | HDAC3 (0.50) | HSP90AA1NPSR1CFTRCA2CA4 | |
| Potassium Ion SCHEMBL5386445 | 0.81 | HDAC3 (0.46) | HSP90AA1CFTRHDAC3HDAC4HDAC1 | |
| SCHEMBL13587656 | 0.81 | NPSR1 (0.53) | NPSR1TOP1USP2MAPTL3MBTL1 | |
| SCHEMBL9310464 | 0.79 | NPSR1 (0.56) | NPSR1TOP1USP2MAPTL3MBTL1 | |
| SCHEMBL10666125 | 0.79 | POLB (0.49) | USP2MAPTALDH1A1LMNAPKM | |
| SCHEMBL5222945 | 0.78 | HSP90AA1 (0.42) | HSP90AA1USP2CFTRMAPTALDH1A1 | |
| SCHEMBL4139139 | 0.78 | NPSR1 (0.44) | HSP90AA1NPSR1TOP1USP2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011128-A1 | PREPARATION OF PROSTAGLANDIN DERIVATIVES | APTUIT LAURUS PRIVATE LIMITED (IN) | 2012-01-26 | — | — | WO | disclosed |