Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | F7 | P08709 | 7/20 | 0.45 |
| ▸ | F3 | P13726 | 7/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13587656 | 0.98 | NPSR1 (0.53) | NPSR1MAPTRXFP1HDAC3HDAC4 | |
| SCHEMBL431983 | 0.93 | NPSR1 (0.50) | NPSR1MAPTRXFP1HDAC3HDAC4 | |
| Bromide SCHEMBL431069 | 0.91 | NPSR1 (0.49) | NPSR1MAPTRXFP1HDAC3HDAC4 | |
| SCHEMBL11072301 | 0.91 | NPSR1 (0.49) | NPSR1MAPTRXFP1HDAC3HDAC4 | |
| SCHEMBL4139139 | 0.85 | NPSR1 (0.44) | NPSR1MAPTRXFP1HDAC3HDAC4 | |
| SCHEMBL11663970 | 0.85 | ALDH1A1 (0.42) | NPSR1MAPTALDH1A1LMNAHPGD | |
| SCHEMBL16772448 | 0.83 | LMNA (0.49) | ALDH1A1PPARGLMNATSHRPOLB | |
| SCHEMBL8757353 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HSD17B10ALOX15CYP3A4TDP1 | |
| SCHEMBL5743094 | 0.81 | TBXAS1 (0.48) | ALDH1A1PPARGLMNAKDM4ETSHR | |
| SCHEMBL431068 | 0.79 | HSP90AA1 (0.38) | NPSR1MAPTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334736-A | Functionalizing carbohydrate derivatives by base-induced β-eliminatiom forming bioactive derivatives containing hydroxy-diene subunits | UNIVERSITY OF TEXAS SYSTEM BOARD OF REGENTS (US) | 1994-08-02 | — | — | US | disclosed |