Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.76 |
| ▸ | MEN1 | O00255 | 7/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.76 |
| ▸ | THRA | P10827 | 7/20 | 0.76 |
| ▸ | LMNA | P02545 | 5/20 | 0.76 |
| ▸ | PPARG | P37231 | 5/20 | 0.76 |
| ▸ | USP2 | O75604 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.76 |
| ▸ | TTR | P02766 | 2/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.76 |
| ▸ | RXRA | P19793 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.76 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | HTR1A | P08908 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369341 | 0.90 | THRB (0.76) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL8369339 | 0.90 | THRB (0.76) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL9746882 | 0.88 | THRB (0.74) | THRBMEN1KMT2ATHRALMNA | |
| Hydrochloric Acid SCHEMBL8825447 | 0.88 | THRB (0.74) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL9748040 | 0.88 | THRB (0.74) | THRBMEN1KMT2ATHRALMNA | |
| Hydrochloric Acid SCHEMBL8825443 | 0.88 | THRB (0.74) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL25773005 | 0.88 | THRB (0.82) | THRBMEN1KMT2ATHRALMNA | |
| Hydrochloric Acid SCHEMBL10877383 | 0.87 | THRB (0.73) | THRBMEN1KMT2ATHRALMNA | |
| Hydrochloric Acid SCHEMBL10877373 | 0.87 | THRB (0.73) | THRBMEN1KMT2ATHRALMNA | |
| Levothyroxine SCHEMBL23098 | 0.86 | THRB (1.00) | THRBMEN1KMT2ATHRALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170020995-A1 | Serine Protease Primary Hemostatic Agent | WORTHAM LEON (US) | 2017-01-26 | — | — | US | disclosed |
| WO-2009126841-A1 | ENZYMATIC BIOSENSORS WITH ENHANCED ACTIVITY RETENTION FOR DETECTION OF ORGANIC COMPOUNDS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-10-15 | — | — | WO | disclosed |
| US-20020103139-A1 | Solid self-emulsifying controlled release drug delivery system composition for enhanced delivery of water insoluble phytosterols and other hydrophobic natural compounds for body weight and cholestrol level control | ALPHARX INC. (CA) | 2002-08-01 | — | — | US | disclosed |
| EP-0171871-A1 | A method for determining the unsaturated binding capacity of a serum protein | WARNER-LAMBERT COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| US-4225784-A | Covalently bound biological substances to plastic materials and use in radioassay | SMITH KLINE INSTRUMENTS, INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4066410-A | RADIOACTIVE HORMONE BINDS TO ANTIBODIES | NUCLEAR-MEDICAL LABORATORIES, INC. (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103139-A1 | Solid self-emulsifying controlled release drug delivery system composition for enhanced delivery of water insoluble phytosterols and other hydrophobic natural compounds for body weight and cholestrol level control | CETP, CYP46A1, NPC1L1 | THRB 3653/4885MEN1 3723/4885KMT2A 2746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.