SCHEMBL4311283

SCHEMBL4311283

C[n+]1ccc(-c2cc3ccc(N(CCO)CCO)cc3oc2=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.55
MAPT P10636 9/20 0.46
MEN1 O00255 8/20 0.46
KMT2A Q03164 8/20 0.46
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 5/20 0.46
RAB9A P51151 5/20 0.46
NPC1 O15118 5/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
LMNA P02545 3/20 0.46
HTT P42858 3/20 0.46
USP2 O75604 3/20 0.46
HPGD P15428 5/20 0.45
ESR2 Q92731 2/20 0.45
ATM Q13315 3/20 0.44
CYP1A2 P05177 1/20 0.44
MAOB P27338 1/20 0.44
CYP2C19 P33261 1/20 0.44
SLC16A3 O15427 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4299398 0.89 CYP19A1 (0.48) CYP19A1MAPTMEN1KMT2AALDH1A1
SCHEMBL4309491 0.88 CYP19A1 (0.52) CYP19A1MAPTMEN1KMT2AALDH1A1
SCHEMBL4298669 0.88 CYP19A1 (0.73) CYP19A1MAPTMEN1KMT2AALDH1A1
Bromide SCHEMBL4301866 0.87 CYP19A1 (0.71) CYP19A1MAPTMEN1KMT2AALDH1A1
SCHEMBL4307998 0.84 SLC16A3 (0.52) CYP19A1MAPTMEN1KMT2AALDH1A1
Sulfuric Acid SCHEMBL4298727 0.83 CYP19A1 (0.62) CYP19A1MAPTMEN1KMT2AALDH1A1
SCHEMBL4309419 0.83 CYP19A1 (0.47) CYP19A1MAPTMEN1KMT2AALDH1A1
SCHEMBL4302791 0.83 ACHE (0.53) CYP19A1MAPTMEN1KMT2AALDH1A1
Bromide SCHEMBL4299197 0.83 SLC16A3 (0.51) CYP19A1MAPTMEN1KMT2AALDH1A1
SCHEMBL4304320 0.82 NPC1 (0.46) CYP19A1MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009124800-A1 CATIONIC DIRECT DYES AND AGENTS FOR DYEING FIBERS CONTAINING KERATIN HENKEL AG & CO. KGAA (DE) 2009-10-15 WO claimed
WO-2009124800-A1 CATIONIC DIRECT DYES AND AGENTS FOR DYEING FIBERS CONTAINING KERATIN HENKEL AG & CO. KGAA (DE) 2009-10-15 WO disclosed
WO-2009124800-A1 CATIONIC DIRECT DYES AND AGENTS FOR DYEING FIBERS CONTAINING KERATIN HENKEL AG & CO. KGAA (DE) 2009-10-15 WO disclosed