Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.79 |
| ▸ | MAPT | P10636 | 13/20 | 0.69 |
| ▸ | MEN1 | O00255 | 9/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | HTT | P42858 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | USP2 | O75604 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | CASP7 | P55210 | 2/20 | 0.61 |
| ▸ | HBB | P68871 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869279 | 0.99 | CYP19A1 (0.77) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869300 | 0.99 | CYP19A1 (0.77) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869499 | 0.97 | CYP19A1 (0.75) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869326 | 0.96 | CYP19A1 (0.73) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869264 | 0.96 | CYP19A1 (0.73) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869643 | 0.94 | CYP19A1 (0.70) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869529 | 0.94 | CYP19A1 (0.70) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869506 | 0.93 | CYP19A1 (0.86) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869433 | 0.93 | CYP19A1 (0.68) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3851202 | 0.92 | CYP19A1 (0.71) | CYP19A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569694-B2 | Coumarin compound, material for light emitting device and organic electroluminescent device | CHISSO CORPORATION (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7569694-B2 | Coumarin compound, material for light emitting device and organic electroluminescent device | CHISSO CORPORATION (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7569694-B2 | Coumarin compound, material for light emitting device and organic electroluminescent device | CHISSO CORPORATION (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | JNC CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | JNC CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | JNC CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | TRPA1, CYP3A4, UGT1A10 | CYP19A1 733/4885MAPT 1624/4885MEN1 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.