Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4317058 | 0.98 | PPARA (0.45) | PPARAPPARGKAT8BIDMCL1 | |
| SCHEMBL28818176 | 0.91 | PPARA (0.48) | PPARAPPARGKAT8BIDMCL1 | |
| SCHEMBL21670763 | 0.89 | F7 (0.53) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL9558191 | 0.86 | PPARA (0.43) | PPARAPPARGKAT8BIDMCL1 | |
| SCHEMBL1439030 | 0.86 | GABRP (0.48) | PPARAPPARGKAT8BIDMCL1 | |
| SCHEMBL14989184 | 0.85 | KAT8 (0.51) | PPARAPPARGKAT8BIDMCL1 | |
| SCHEMBL14989183 | 0.85 | KAT8 (0.51) | PPARAPPARGKAT8BIDMCL1 | |
| SCHEMBL14989185 | 0.85 | KAT8 (0.51) | PPARAPPARGKAT8BIDMCL1 | |
| SCHEMBL14989165 | 0.85 | KAT8 (0.51) | PPARAPPARGKAT8BIDMCL1 | |
| SCHEMBL14989188 | 0.85 | KAT8 (0.51) | PPARAPPARGKAT8BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |