Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625344 | 0.91 | HRH1 (0.49) | HRH1HSD17B10HTR6CYP1A2CYP2D6 | |
| SCHEMBL1436947 | 0.85 | HTR6 (0.51) | HRH1HSD17B10HTR6CYP1A2CYP2D6 | |
| SCHEMBL29849641 | 0.85 | HTR6 (0.51) | HRH1HSD17B10HTR6CYP1A2CYP2D6 | |
| SCHEMBL5788565 | 0.83 | CYP1A2 (0.35) | HRH1HSD17B10HTR6CYP1A2CYP2D6 | |
| SCHEMBL2338975 | 0.82 | HTR6 (0.56) | HTR6 | |
| SCHEMBL31121639 | 0.82 | HTR6 (0.56) | HTR6 | |
| SCHEMBL11223271 | 0.75 | HTR6 (0.47) | HTR6CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL3868123 | 0.75 | HTR6 (0.53) | HTR6ALDH1A1LMNA | |
| SCHEMBL3874874 | 0.75 | HTR6 (0.53) | HTR6ALDH1A1LMNA | |
| SCHEMBL29485678 | 0.74 | HRH1 (0.73) | HRH1HSD17B10CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541481-B2 | Monocyclopentadienyl complex | BASELL POLYOLEFIN GMBH (DE) | 2009-06-02 | — | — | US | disclosed |
| CN-100334098-C | New monocyclopentadienyl complex | BASELL POLYOLEFINE GMBH (DE) | 2007-08-29 | — | — | CN | disclosed |
| US-20070155918-A1 | Monocyclopentadienyl complex | BASELL POLYOLEFINE GMBH (DE) | 2007-07-05 | — | — | US | disclosed |
| US-20060089253-A1 | Monocyclopentadienyl complexes | BASELL POLYOLEFINE GMBH (DE) | 2006-04-27 | — | — | US | disclosed |
| EP-1534724-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2006-03-08 | — | — | EP | disclosed |
| CN-1688594-A | New monocyclopentadienyl complex | BASELL POLYOLEFINE GMBH (DE) | 2005-10-26 | — | — | CN | disclosed |
| EP-1534724-A2 | MONOCYCLOPENTADIENYL COMPLEXES | Basell Polyolefine GmbH (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004020479-A2 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-03-11 | — | — | WO | disclosed |
| US-4127578-A | Diene intermediates for indantetrols | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4092318-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4044040-A | HYPERTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155918-A1 | Monocyclopentadienyl complex | COASY, PCBP1, ORC3 | HRH1 4291/4885HSD17B10 566/4885HTR6 3910/4885 |
| US-20060089253-A1 | Monocyclopentadienyl complexes | COASY, PCBP1, ORC3 | HRH1 3967/4885HSD17B10 673/4885HTR6 3147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.