SCHEMBL431535

SCHEMBL431535

c1ccc(Nc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.77
HSD17B10 Q99714 5/20 0.77
ALOX12 P18054 4/20 0.77
L3MBTL1 Q9Y468 4/20 0.77
TSHR P16473 4/20 0.77
TDP1 Q9NUW8 4/20 0.77
ALOX15 P16050 2/20 0.77
PTGS1 P23219 1/20 0.77
SLC6A2 P23975 1/20 0.77
MAPK1 P28482 1/20 0.77
PTGS2 P35354 1/20 0.77
HTR2B P41595 1/20 0.77
CYP3A4 P08684 5/20 0.59
MAPT P10636 5/20 0.59
HPGD P15428 3/20 0.59
HTT P42858 2/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
MEN1 O00255 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14160281 1.00 ALDH1A1 (0.77) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL20445899 1.00 ALDH1A1 (0.77) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL11961725 1.00 ALDH1A1 (0.77) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL14160282 1.00 ALDH1A1 (0.77) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL12367618 1.00 ALDH1A1 (0.77) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL10079561 1.00 ALDH1A1 (0.77) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL14160278 1.00 ALDH1A1 (0.77) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL17965666 0.97 ALDH1A1 (0.81) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL5370467 0.97 ALDH1A1 (0.71) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL428698 0.97 ALDH1A1 (0.71) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2083 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115417993-A SiCOBN ceramic precursor and preparation method of ceramic 哈尔滨工业大学 2022-12-02 CN claimed
CN-112735840-B Triphenylphosphino porous organic polymer and graphene aerogel composite, preparation method thereof and application of supercapacitor 云南大学 2022-03-01 CN claimed
CN-112735840-A Triphenylphosphino porous organic polymer and graphene aerogel composite, preparation method thereof and application of supercapacitor 云南大学 2021-04-30 CN claimed
US-10032988-B2 Anthracene-containing derivative, production process thereof and organic electroluminescent display device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-07-24 US claimed
CN-105237520-B A kind of compound-material containing pyrazoline structure and its application 江苏三月光电科技有限公司 2018-01-30 CN claimed
CN-104861152-B A kind of polyurethane with memristor performance and its preparation method and application 黑龙江大学 2017-10-10 CN claimed
US-20160064668-A1 ANTHRACENE-CONTAINING DERIVATIVE, PRODUCTION PROCESS THEREOF AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-03-03 US claimed
CN-105237520-A Compound material containing pyrazoline structure and application of compound material JIANGSU SANYUE PHOTOELECTRIC TECHNOLOGY CO LTD 2016-01-13 CN claimed
CN-105130971-A Bithiophene pyrrolic compound containing diphenyl-4-phenylamine diphenyl diamine and preparation as well as polymer and preparation method and application UNIV HEILONGJIANG 2015-12-09 CN claimed
EP-1294695-A2 SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS Ortho-McNeil Pharmaceutical, Inc. (US) 2003-03-26 EP claimed
WO-2001085694-A2 SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-11-15 WO claimed
EP-0694057-B1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEM CO INC (US) 2000-03-01 EP claimed
EP-0694057-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-31 EP claimed
WO-1994024235-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-10-27 WO claimed
US-5310491-A Alkyl substituted 1,2-dihydroquinoline reacted with diarylamine UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-05-10 US claimed
CN-122029975-A Composition for organic light emitting device and organic light emitting device including the same LT素材株式会社 2026-05-12 CN disclosed
US-12604659-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2026-04-14 US disclosed
EP-0694057-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-31 EP disclosed
WO-1994024235-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-10-27 WO disclosed
US-5310491-A Alkyl substituted 1,2-dihydroquinoline reacted with diarylamine UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-05-10 US disclosed