Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060954 | 0.81 | — | — | |
| SCHEMBL16290202 | 0.78 | — | — | |
| SCHEMBL24033863 | 0.72 | CA12 (0.49) | L3MBTL1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL24033543 | 0.72 | CA12 (0.41) | L3MBTL1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13423070 | 0.69 | — | — | |
| SCHEMBL14348162 | 0.68 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3644558 | 0.67 | TSHR (0.54) | MEN1KMT2ACTNNB1 | |
| SCHEMBL24192978 | 0.65 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL253271 | 0.65 | — | — | |
| SCHEMBL9986002 | 0.64 | L3MBTL1 (0.79) | CTHL3MBTL1ALDH1A1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2056844-A2 | NOVEL MACROLIDES AND KETOLIDES HAVING ANTIMICROBIAL ACTIVITY | Wockhardt Research Centre (IN) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008023248-A2 | NOVEL MACROLIDES AND KETOLIDES HAVING ANTIMICROBIAL ACTIVITY | WOCKHARDT RESEARCH CENTRE (IN) | 2008-02-28 | — | — | WO | disclosed |