Vanillic Acid

Vanillic Acid

SCHEMBL431677

CCOC(=O)c1ccc(O)c(OC)c1.COc1cc(C(=O)O)ccc1O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 1/20 0.88
HTT P42858 1/20 0.73
KDM4E B2RXH2 1/20 0.69
POLB P06746 1/20 0.69
HDAC6 Q9UBN7 1/20 0.69
CA12 O43570 2/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
CA7 P43166 2/20 0.62
CA9 Q16790 2/20 0.62
CA14 Q9ULX7 2/20 0.62
TSHR P16473 1/20 0.57
RAB9A P51151 2/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
SLC22A6 Q4U2R8 1/20 0.57
SLC22A8 Q8TCC7 1/20 0.57
CYP1A2 P05177 1/20 0.55
HSP90AA1 P07900 1/20 0.55
HSP90AB1 P08238 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155638 0.94 HSD17B2 (1.00) HSD17B2HTTKDM4EPOLBHDAC6
Benzocaine SCHEMBL18740972 0.92 HSD17B2 (0.74) HSD17B2HTTKDM4EPOLBHDAC6
Alcohol SCHEMBL27898607 0.91 HSD17B2 (0.94) HSD17B2HTTKDM4EPOLBHDAC6
SCHEMBL11884205 0.90 HSD17B2 (0.86) HSD17B2HTTKDM4EPOLBHDAC6
SCHEMBL20456421 0.86 HSD17B2 (0.83) HSD17B2HTTKDM4EPOLBHDAC6
Vanillic Acid SCHEMBL26179 0.86 HTT (1.00) HSD17B2HTTKDM4EPOLBHDAC6
Vanillic Acid SCHEMBL9711598 0.86 HTT (1.00) HSD17B2HTTKDM4EPOLBHDAC6
Vanillic Acid SCHEMBL29378740 0.86 HTT (1.00) HSD17B2HTTKDM4EPOLBHDAC6
Vanillic Acid SCHEMBL18334646 0.84 HTT (0.96) HSD17B2HTTKDM4EPOLBHDAC6
Vanillic Acid SCHEMBL6697041 0.84 HTT (0.96) HSD17B2HTTKDM4EPOLBHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018144900-A1 SMALL MOLECULE ANTAGONISTS OF SUMO RELATED MODIFICATION OF CRMP2 AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2018-08-09 WO disclosed
EP-2595642-A2 COMPOSITIONS COMPRISING DERIVATIVES OF ESSENTIAL OIL COMPOUNDS AND USE IN PERSONAL CARE PRODUCTS The Procter and Gamble Company (US) 2013-05-29 EP disclosed
WO-2012012385-A2 COMPOSITIONS COMPRISING DERIVATIVES OF ESSENTIAL OIL COMPOUNDS AND USE IN PERSONAL CARE PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2012-01-26 WO disclosed