Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vanillic Acid SCHEMBL431677 | 0.92 | HSD17B2 (0.88) | HSD17B2HTTCYP1A2KDM4EPOLB | |
| SCHEMBL155638 | 0.86 | HSD17B2 (1.00) | HSD17B2HTTCYP1A2LMNACYP3A4 | |
| Procaine SCHEMBL18741023 | 0.85 | CYP2D6 (0.69) | HSD17B2HTTCYP1A2LMNACYP3A4 | |
| Alcohol SCHEMBL27898607 | 0.83 | HSD17B2 (0.94) | HSD17B2HTTCYP1A2KDM4EPOLB | |
| Benzocaine SCHEMBL8215681 | 0.83 | LMNA (0.86) | HTTCYP1A2LMNACYP3A4MAOA | |
| SCHEMBL11884205 | 0.82 | HSD17B2 (0.86) | HSD17B2HTTCYP1A2KDM4EPOLB | |
| Vanillic Acid SCHEMBL27955356 | 0.81 | HTT (0.93) | HSD17B2HTTCYP1A2LMNAKDM4E | |
| Benzocaine SCHEMBL15200678 | 0.81 | LMNA (0.96) | HSD17B2HTTCYP1A2LMNACYP3A4 | |
| Vanillic Acid SCHEMBL26179 | 0.81 | HTT (1.00) | HSD17B2HTTCYP1A2LMNAKDM4E | |
| Vanillic Acid SCHEMBL9711598 | 0.81 | HTT (1.00) | HSD17B2HTTCYP1A2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180297966-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | INNOVATIVE ANESTHETICS, LLC | 2018-10-18 | — | — | US | claimed |
| WO-2017066787-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | LEBEDYEVA IRYNA O (US) | 2017-04-20 | — | — | WO | claimed |
| US-20180297966-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | INNOVATIVE ANESTHETICS, LLC | 2018-10-18 | — | — | US | disclosed |
| WO-2017066787-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | LEBEDYEVA IRYNA O (US) | 2017-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180297966-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | TRPA1, TRPV1, AQP1 | HSD17B2 273/4885HTT 437/4885CYP1A2 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.