SCHEMBL43168

SCHEMBL43168

O=C(O)C1Cc2ccccc2CN1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.58
MAPT P10636 1/20 0.58
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
EGLN1 Q9GZT9 1/20 0.52
PRCP P42785 1/20 0.52
OPRM1 P35372 1/20 0.48
OPRD1 P41143 1/20 0.48
OPRK1 P41145 1/20 0.48
PNMT P11086 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288260 1.00 GAA (0.58) GAAMAPTMEN1KMT2AEGLN1
SCHEMBL29350565 1.00 GAA (0.58) GAAMAPTMEN1KMT2AEGLN1
SCHEMBL29398238 1.00 GAA (0.58) GAAMAPTMEN1KMT2AEGLN1
SCHEMBL29350888 1.00 GAA (0.58) GAAMAPTMEN1KMT2AEGLN1
SCHEMBL288272 1.00 GAA (0.58) GAAMAPTMEN1KMT2AEGLN1
Bromide SCHEMBL8763315 0.98 GAA (0.56) GAAMAPTMEN1KMT2AEGLN1
Hydrochloric Acid SCHEMBL7272493 0.98 GAA (0.56) GAAMAPTMEN1KMT2AEGLN1
Hydrochloric Acid SCHEMBL1202518 0.98 GAA (0.56) GAAMAPTMEN1KMT2AEGLN1
Hydrochloric Acid SCHEMBL32677098 0.98 GAA (0.56) GAAMAPTMEN1KMT2AEGLN1
SCHEMBL28412655 0.98 GAA (0.56) GAAMAPTMEN1KMT2AEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13113 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS ENDEVICA BIO INC (US) 2026-04-09 US claimed
US-12583889-B2 Cell penetrating peptides OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2026-03-24 US claimed
US-12559523-B2 Compositions comprising chemerin analogs and methods of use OKYO PHARMA LIMITED (GG) 2026-02-24 US claimed
US-12521455-B2 Kisspeptin receptor (KISS1R) targeted therapeutics and uses thereof RADIONETICS ONCOLOGY, INC. (US) 2026-01-13 US claimed
EP-4665374-A1 METHODS OF PREVENTING AND/OR TREATING SIDE EFFECTS ASSOCIATED WITH ANTI-CANCER AGENTS USING NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS WITH ANTI-GDF-15 ANTIBODIES Endevica Bio, Inc. (US) 2025-12-24 EP claimed
WO-2025245288-A1 NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS AND USES THEREOF ENDEVICA BIO, INC. (US) 2025-11-27 WO claimed
WO-2025245279-A1 NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR AGONISTS AND USE THEREFORE IN TREATMENT OF ADDICTION AND/OR PAIN ENDEVICA BIO, INC. (US) 2025-11-27 WO claimed
WO-2025217074-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2025-10-16 WO claimed
US-20250312499-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-10-09 US claimed
US-12428447-B2 Peptide-based non-proteinaceous cargo delivery FELDAN BIO INC. (CA) 2025-09-30 US claimed
EP-0236734-A2 5-Amino-4-hydroxyvaleryl derivatives substituted by s-containing groups CIBA-GEIGY AG (CH) 1987-09-16 EP claimed
EP-0049605-B1 SUBSTITUTED ACYL DERIVATIVES OF 1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACIDS, SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THE DERIVATIVES OR SALTS, AND THE PRODUCTION OF THE SAME WARNER-LAMBERT COMPANY (US) 1987-03-18 EP claimed
US-4623715-A ANTIDEPRESSANTS HOECHST AKTIENGESELLESCHAFT (DE) 1986-11-18 US claimed
US-4621073-A Cyclic peptides having somatostatin activity HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-04 US claimed
EP-0184550-A2 5-Amino-4-hydroxy valeryl amide derivatives CIBA-GEIGY AG (CH) 1986-06-11 EP claimed
EP-0179332-A2 ZNS-active peptides acting on the cholinergetic system HOECHST AKTIENGESELLSCHAFT (DE) 1986-04-30 EP claimed
EP-0012845-B1 TETRAHYDROISOQUINOLINE COMPOUNDS, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Tanabe Seiyaku Co., Ltd. (JP) 1983-06-22 EP claimed
US-4344949-A Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids WARNER-LAMBERT COMPANY (US) 1982-08-17 US claimed
EP-0049605-A1 Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids, salts thereof, pharmaceutical compositions containing the derivatives or salts, and the production of the same WARNER-LAMBERT COMPANY (US) 1982-04-14 EP claimed
EP-0012845-A1 Tetrahydroisoquinoline compounds, process for preparing same and pharmaceutical compositions containing them Tanabe Seiyaku Co., Ltd. (JP) 1980-07-09 EP claimed