Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | PRF1 | P14222 | 1/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161845 | 0.88 | OPRD1 (0.66) | OPRD1GRM5MEN1KMT2AHRH3 | |
| SCHEMBL13611935 | 0.81 | TYRO3 (0.43) | OPRD1MEN1KMT2AHRH3PRF1 | |
| SCHEMBL13626332 | 0.81 | HRH3 (0.54) | OPRD1GRM5HRH3TYRO3NTRK2 | |
| SCHEMBL15571028 | 0.79 | PRF1 (0.51) | GRM5MEN1KMT2APRF1DDB1 | |
| SCHEMBL677630 | 0.78 | GRM5 (0.58) | OPRD1GRM5MEN1KMT2A | |
| SCHEMBL22005067 | 0.77 | NOTUM (0.50) | OPRD1MEN1KMT2AHRH3 | |
| SCHEMBL12038178 | 0.77 | MEN1 (0.54) | GRM5MEN1KMT2ADDB1CRBN | |
| SCHEMBL2386047 | 0.77 | MEN1 (0.54) | GRM5MEN1KMT2ADDB1CRBN | |
| SCHEMBL30561539 | 0.77 | MEN1 (0.54) | GRM5MEN1KMT2ADDB1CRBN | |
| SCHEMBL6109465 | 0.77 | GRM5 (0.56) | GRM5HRH3TYRO3NTRK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |