Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878863 | 0.97 | SIGMAR1 (0.48) | SIGMAR1CYP1A2LMNAMAPK1HTT | |
| SCHEMBL224496 | 0.94 | SIGMAR1 (0.39) | SIGMAR1CYP1A2LMNAMAPK1HTT | |
| SCHEMBL10348157 | 0.89 | SIGMAR1 (0.60) | SIGMAR1CYP1A2KDM5AKDM4CPHF8 | |
| SCHEMBL10417810 | 0.89 | SIGMAR1 (0.60) | SIGMAR1CYP1A2KDM5AKDM4CPHF8 | |
| SCHEMBL2159790 | 0.87 | CYP1A2 (0.50) | SIGMAR1CYP1A2LMNAMAPK1HTT | |
| SCHEMBL28973173 | 0.87 | SIGMAR1 (0.37) | SIGMAR1CYP1A2LMNAMAPK1HTT | |
| SCHEMBL17592459 | 0.87 | CYP1A2 (0.50) | SIGMAR1CYP1A2LMNAMAPK1HTT | |
| SCHEMBL4811849 | 0.87 | SIGMAR1 (0.37) | SIGMAR1CYP1A2LMNAMAPK1HTT | |
| SCHEMBL2159788 | 0.87 | CYP1A2 (0.50) | SIGMAR1CYP1A2LMNAMAPK1HTT | |
| SCHEMBL4811842 | 0.87 | SIGMAR1 (0.37) | SIGMAR1CYP1A2KDM5AKDM7AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596041-A1 | POLYURETHANE HAVING HIGH LIGHT REFRACTION | Bayer Intellectual Property GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010526-A1 | POLYURETHANE HAVING HIGH LIGHT REFRACTION | BAYER MATERIALSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |