Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | DRD5 | P21918 | 7/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 6/20 | 0.47 |
| ▸ | DRD4 | P21917 | 5/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4323244 | 0.92 | DRD1 (0.50) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL4316001 | 0.85 | SLC6A2 (0.43) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL4316512 | 0.73 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4328719 | 0.70 | SLC6A4 (0.49) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL4461630 | 0.70 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4323108 | 0.69 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4458919 | 0.69 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4338598 | 0.69 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4459508 | 0.69 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9325693 | 0.68 | SIGMAR1 (0.46) | DRD1DRD5DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |