⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4315823 | 0.88 | — | — | |
| SCHEMBL834366 | 0.83 | — | — | |
| SCHEMBL4315706 | 0.80 | — | — | |
| SCHEMBL4324678 | 0.73 | — | — | |
| SCHEMBL1846560 | 0.71 | — | — | |
| SCHEMBL6900823 | 0.71 | ALDH1A1 (0.37) | — | |
| SCHEMBL6900820 | 0.71 | ALDH1A1 (0.37) | — | |
| SCHEMBL1230616 | 0.71 | SLC22A2 (0.31) | — | |
| SCHEMBL3226595 | 0.71 | SLC22A2 (0.31) | — | |
| SCHEMBL8189 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215650-A2 | Substituted bridged-diazabicycloalkyl quinolone carboxylic acids | PFIZER INC. (US) | 1987-03-25 | — | — | EP | claimed |
| US-7557117-B2 | 4-oxoimidazolidine-2-spiropiperidine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20080275064-A1 | Substituted Pyrimidines as Adenosine Receptor Antagonists | ALMIRALL, S.A. (ES) | 2008-11-06 | — | — | US | disclosed |
| EP-1420020-B1 | 4-OXOIMIDAZOLIDINE-2-SPIROPIPERIDINE DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2008-05-28 | — | — | EP | disclosed |
| US-20070078153-A1 | 4-Oxoimidazolidine-2-spiropiperidine derivatives | MSD K.K. (JP) | 2007-04-05 | — | — | US | disclosed |
| US-7192964-B2 | 4-oxoimidazolidine-2-spiropiperidine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-6969712-B2 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| US-20050004363-A1 | 4-oxoimidazolidine-2-spiropiperidine derivatives | MSD K.K. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1420020-A1 | 4-OXOIMIDAZOLIDINE-2-SPIROPIPERIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-20040044056-A1 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1342717-A1 | BENZIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |