Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27603115 | 0.93 | HTR6 (0.55) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL4313175 | 0.92 | HTR6 (0.57) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL30735820 | 0.89 | HTR6 (0.66) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL3609792 | 0.89 | HTR6 (0.66) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| Hydrochloric Acid SCHEMBL6047117 | 0.87 | HTR6 (0.64) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL1380982 | 0.84 | HTR6 (0.57) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL3617611 | 0.84 | HTR6 (0.57) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL1380651 | 0.84 | HTR6 (0.60) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| Hydrochloric Acid SCHEMBL1376887 | 0.83 | HTR6 (0.56) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| Hydrochloric Acid SCHEMBL6047112 | 0.83 | HTR6 (0.56) | HTR6HTR1AHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572787-B2 | Substituted naphthalene sulfonamides | BIOVITRUM AB (SE) | 2009-08-11 | — | — | US | disclosed |