Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.51 |
| ▸ | CPT1A | P50416 | 1/20 | 0.51 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578022 | 0.93 | CPT2 (0.45) | CPT2CPT1ACPT1BHIF1AEPAS1 | |
| SCHEMBL4333770 | 0.90 | CPT2 (0.53) | CPT2CPT1ACPT1BHIF1AEPAS1 | |
| SCHEMBL4335570 | 0.89 | CPT2 (0.52) | CPT2CPT1ACPT1BS1PR1MAPT | |
| SCHEMBL4331924 | 0.88 | CPT2 (0.51) | CPT2CPT1ACPT1BS1PR1MAPT | |
| SCHEMBL4340728 | 0.83 | NPC1 (0.48) | CPT2CPT1ACPT1BMAPTKDM4E | |
| SCHEMBL13578024 | 0.83 | CPT2 (0.47) | CPT2CPT1ACPT1BMAPTKDM4E | |
| SCHEMBL4330821 | 0.83 | CPT2 (0.48) | CPT2CPT1ACPT1BNPC1POLB | |
| SCHEMBL4340830 | 0.83 | NPC1 (0.48) | CPT2CPT1ACPT1BHIF1AEPAS1 | |
| SCHEMBL13577923 | 0.83 | CPT2 (0.47) | CPT2CPT1ACPT1BMAPTNPC1 | |
| SCHEMBL13578018 | 0.82 | CPT2 (0.46) | CPT2CPT1ACPT1BMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | claimed |
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |