Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19626732 | 0.79 | RECQL (0.62) | RECQLTSHRHTTALDH1A1HPGD | |
| SCHEMBL601034 | 0.77 | HTT (0.68) | LMNARECQLTSHRHTTALDH1A1 | |
| SCHEMBL10076588 | 0.77 | RECQL (0.68) | LMNARECQLTSHRHTTALDH1A1 | |
| SCHEMBL19627010 | 0.75 | GFER (0.59) | LMNARECQLTSHRHTTALDH1A1 | |
| SCHEMBL1943940 | 0.75 | KMT2A (0.57) | LMNATSHRALDH1A1HPGDMAPT | |
| SCHEMBL155616 | 0.74 | RECQL (0.62) | LMNARECQLTSHRHTTALDH1A1 | |
| SCHEMBL12468441 | 0.74 | RECQL (0.56) | LMNARECQLTSHRHTTALDH1A1 | |
| SCHEMBL3088586 | 0.73 | RECQL (0.63) | LMNARECQLTSHRHTTALDH1A1 | |
| SCHEMBL1020685 | 0.73 | RECQL (0.59) | LMNARECQLTSHRHTTALDH1A1 | |
| SCHEMBL3322009 | 0.72 | HSD17B1 (0.68) | RECQLTSHRHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |