⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360289 | 0.87 | — | — | |
| SCHEMBL11910721 | 0.82 | — | — | |
| SCHEMBL19215724 | 0.82 | — | — | |
| SCHEMBL30749717 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL30825020 | 0.78 | — | — | |
| SCHEMBL5608675 | 0.72 | — | — | |
| SCHEMBL16731979 | 0.58 | — | — | |
| SCHEMBL4438485 | 0.56 | — | — | |
| SCHEMBL22489 | 0.56 | — | — | |
| SCHEMBL10713958 | 0.56 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028495-B | The preparation method of pazopanib hydrochloride | 济南爱思医药科技有限公司 | 2019-12-03 | — | — | CN | claimed |
| CN-110028495-A | The environment-friendly preparation method thereof of pazopanib hydrochloride | 济南爱思医药科技有限公司 | 2019-07-19 | — | — | CN | claimed |
| CN-104831418-B | Poly(crown ether) composite nanometer fibrous material, and preparation method and application thereof | 天津医科大学 | 2017-01-18 | — | — | CN | claimed |
| CN-106009785-A | Conductive pearlescent pigment and preparation method thereof | 林中 | 2016-10-12 | — | — | CN | claimed |
| CN-110028495-B | The preparation method of pazopanib hydrochloride | 济南爱思医药科技有限公司 | 2019-12-03 | — | — | CN | disclosed |
| CN-110028495-A | The environment-friendly preparation method thereof of pazopanib hydrochloride | 济南爱思医药科技有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-109709239-A | A kind of detection method using the online pre-treatment urine sample of Poly-crown ether functionalized nano-fiber | 天津医科大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-104831418-B | Poly(crown ether) composite nanometer fibrous material, and preparation method and application thereof | 天津医科大学 | 2017-01-18 | — | — | CN | disclosed |
| CN-106190833-A | Culture vessel, gel rubber material and culture systems | 精工爱普生株式会社 | 2016-12-07 | — | — | CN | disclosed |
| CN-106168594-A | Sensor gel and sensor | 精工爱普生株式会社 | 2016-11-30 | — | — | CN | disclosed |
| CN-106168575-A | Sensor gel and sensor | 精工爱普生株式会社 | 2016-11-30 | — | — | CN | disclosed |
| CN-106009784-A | Carbon black coloring pearlescent pigment and preparation method thereof | 林中 | 2016-10-12 | — | — | CN | disclosed |
| CN-106009785-A | Conductive pearlescent pigment and preparation method thereof | 林中 | 2016-10-12 | — | — | CN | disclosed |
| WO-2009137270-A2 | AZETIDINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-11-12 | — | — | WO | disclosed |
| US-4507311-A | Imidazo[1,2-c][1,3]benzodiazepines | CIBA-GEIGY CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| US-4500472-A | CYCLIZATION, DEHYDRATION OF 1-(2-IMIDAZO-2-YLTHIO) PHENYLIMINO THIOCARBONYL) PIPERAZINE) | CIBA-GEIGY CORPORATION (US) | 1985-02-19 | — | — | US | disclosed |
| US-4477379-A | NEUROLEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| US-4460587-A | ANTIPSYCHOTIC AGENTS, ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| US-4444688-A | NEUROLEPTICS | CIBA-GEIGY CORPORATION (US) | 1984-04-24 | — | — | US | disclosed |
| US-4391808-A | NEUROLEPTIC AND ANTIPSYCHOTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-07-05 | — | — | US | disclosed |