Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 8/20 | 0.82 |
| ▸ | P2RY6 | Q15077 | 10/20 | 0.81 |
| ▸ | P2RY2 | P41231 | 9/20 | 0.81 |
| ▸ | P2RY4 | P51582 | 8/20 | 0.81 |
| ▸ | OGT | O15294 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521304 | 1.00 | P2RY14 (0.82) | P2RY14P2RY6P2RY2P2RY4OGT | |
| SCHEMBL1521046 | 0.95 | P2RY14 (0.74) | P2RY14P2RY6P2RY2P2RY4OGT | |
| SCHEMBL1521075 | 0.95 | P2RY14 (0.74) | P2RY14P2RY6P2RY2P2RY4OGT | |
| SCHEMBL23344493 | 0.90 | P2RY14 (1.00) | P2RY14P2RY6P2RY2P2RY4OGT | |
| SCHEMBL15433957 | 0.90 | P2RY14 (1.00) | P2RY14P2RY6P2RY2P2RY4OGT | |
| SCHEMBL14281873 | 0.90 | P2RY14 (1.00) | P2RY14P2RY6P2RY2P2RY4OGT | |
| SCHEMBL12377962 | 0.90 | P2RY14 (1.00) | P2RY14P2RY6P2RY2P2RY4OGT | |
| SCHEMBL1521296 | 0.90 | P2RY14 (1.00) | P2RY14P2RY6P2RY2P2RY4OGT | |
| SCHEMBL20718791 | 0.90 | P2RY14 (1.00) | P2RY14P2RY6P2RY2P2RY4OGT | |
| SCHEMBL16138527 | 0.90 | P2RY14 (1.00) | P2RY14P2RY6P2RY2P2RY4OGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708590-B2 | Crystal structure of human α-N-acetylglucosaminidase | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| EP-2975134-A2 | CRYSTAL STRUCTURE OF HUMAN ALPHA-N-ACETYLGLUCOSAMINIDASE | Shire Human Genetic Therapies, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2596123-B1 | CRYSTAL STRUCTURE OF HUMAN ALPHA-N-ACETYLGLUCOSAMINIDASE | SHIRE HUMAN GENETIC THERAPIES (US) | 2015-11-25 | — | — | EP | disclosed |
| US-20150031112-A1 | Crystal structure of human alpha-n-acetylglucosaminidase | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2015-01-29 | — | — | US | disclosed |
| US-8775146-B2 | Crystal structure of human alpha-N-acetylglucosaminidase | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120021436-A1 | Crystal structure of human alpha-N-acetylglucosaminidase | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2012-01-26 | — | — | US | disclosed |