Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432154 | 1.00 | GSK3B (0.35) | GSK3BGSK3ASCN9AMCHR1MAPT | |
| SCHEMBL431257 | 0.91 | MCHR1 (0.34) | GSK3BGSK3ASCN9AMCHR1MAPT | |
| SCHEMBL431256 | 0.91 | MCHR1 (0.34) | GSK3BGSK3ASCN9AMCHR1MAPT | |
| SCHEMBL432986 | 0.89 | MAPT (0.37) | GSK3BGSK3ASCN9AMCHR1MAPT | |
| SCHEMBL432987 | 0.89 | MAPT (0.37) | GSK3BGSK3ASCN9AMCHR1MAPT | |
| SCHEMBL435039 | 0.88 | MCHR1 (0.34) | GSK3BGSK3ASCN9AMCHR1MAPT | |
| SCHEMBL435038 | 0.88 | MCHR1 (0.34) | GSK3BGSK3ASCN9AMCHR1MAPT | |
| SCHEMBL433488 | 0.88 | EBP (0.36) | GSK3BGSK3ASCN9AMCHR1MAPT | |
| SCHEMBL432023 | 0.88 | GRM5 (0.34) | SCN9AMCHR1PROKR1EBPSIGMAR1 | |
| SCHEMBL434931 | 0.88 | GRM5 (0.34) | SCN9AMCHR1PROKR1EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012366-A1 | PESTICIDAL 3-(ARYLOXY)AZACYCLOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-26 | — | — | WO | claimed |
| WO-2012012366-A1 | PESTICIDAL 3-(ARYLOXY)AZACYCLOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |