Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22039771 | 0.79 | DDB1 (0.36) | CHRNB2CHRNA4CHRNA7CYP2C19CYP1A2 | |
| SCHEMBL22040887 | 0.79 | DDB1 (0.36) | CHRNB2CHRNA4CHRNA7CYP2C19CYP1A2 | |
| SCHEMBL19776738 | 0.79 | SMN1; SMN2 (0.44) | CHRNA7MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL20983529 | 0.79 | SMN1; SMN2 (0.44) | CHRNA7MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL15730210 | 0.79 | SMN1; SMN2 (0.44) | CHRNA7MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1105469 | 0.79 | SMN1; SMN2 (0.44) | CHRNA7MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL15730213 | 0.79 | SMN1; SMN2 (0.44) | CHRNA7MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7591664 | 0.77 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| SCHEMBL7591667 | 0.77 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| SCHEMBL24366579 | 0.76 | CHRNB2 (0.64) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073690-A1 | SYSTEM AND PROCESS FOR TOBACCOLESS NICOTINE DELIVERY | UMAGINATION LABS, L.P. (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2008103818-A1 | THERAPEUTIC COTININE COMPOSITIONS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION (US) | 2008-08-28 | — | — | WO | disclosed |