Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321880 | 0.83 | SLC6A4 (0.42) | KMT2AESR1SMN1; SMN2SLC6A4SLC6A2 | |
| SCHEMBL4316588 | 0.82 | KMT2A (0.43) | KMT2AMEN1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4316957 | 0.80 | SLC6A4 (0.39) | MAPTSLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4326421 | 0.79 | SLC6A4 (0.40) | KMT2AMEN1POLBSLC6A4SLC6A2 | |
| SCHEMBL4451508 | 0.79 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4323128 | 0.75 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4326357 | 0.75 | SLC6A4 (0.50) | MAPTSLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4325036 | 0.74 | SLC6A2 (0.50) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4468394 | 0.74 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4331733 | 0.74 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | claimed |
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |