Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336739 | 0.87 | KMT2A (0.33) | KMT2ASLC6A2SLC6A4SLC6A3KDM2B | |
| SCHEMBL4316512 | 0.86 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4322610 | 0.82 | KMT2A (0.42) | KMT2ASLC6A2SLC6A4SLC6A3RAB9A | |
| SCHEMBL4328719 | 0.79 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4316957 | 0.79 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL4321880 | 0.79 | SLC6A4 (0.42) | KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4326421 | 0.79 | SLC6A4 (0.40) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL4331669 | 0.76 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL4462120 | 0.76 | CA2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4336742 | 0.76 | KMT2A (0.31) | KMT2ASLC6A4RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |