Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | PRNP | P04156 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | F13A1 | P00488 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12038476 | 0.84 | RXFP1 (0.64) | RXFP1ALDH1A1LMNARECQLPRNP | |
| SCHEMBL10600466 | 0.81 | RXFP1 (0.77) | RXFP1ALDH1A1LMNARECQLPRNP | |
| SCHEMBL10595901 | 0.81 | RXFP1 (0.77) | RXFP1ALDH1A1LMNARECQLPRNP | |
| SCHEMBL10597136 | 0.81 | RXFP1 (0.77) | RXFP1ALDH1A1LMNARECQLPRNP | |
| SCHEMBL10598276 | 0.81 | RXFP1 (0.77) | RXFP1ALDH1A1LMNARECQLPRNP | |
| SCHEMBL10597870 | 0.81 | RXFP1 (0.77) | RXFP1ALDH1A1LMNARECQLPRNP | |
| SCHEMBL10598573 | 0.81 | RXFP1 (0.77) | RXFP1ALDH1A1LMNARECQLPRNP | |
| SCHEMBL10598170 | 0.81 | RXFP1 (0.77) | RXFP1ALDH1A1LMNARECQLPRNP | |
| SCHEMBL10800242 | 0.81 | RXFP1 (0.77) | RXFP1ALDH1A1LMNARECQLPRNP | |
| SCHEMBL10599428 | 0.81 | RXFP1 (0.77) | RXFP1ALDH1A1LMNARECQLPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596065-B1 | LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES | BECTON DICKINSON CO (US) | 2018-03-07 | — | — | EP | disclosed |
| US-8623324-B2 | Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates | AAT BIOQUEST INC. (US) | 2014-01-07 | — | — | US | disclosed |
| EP-2596065-A2 | LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES | Becton, Dickinson and Company (US) | 2013-05-29 | — | — | EP | disclosed |
| US-20120183954-A1 | LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES | AAT BIOQUEST, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| WO-2012012595-A2 | LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES | BECTON, DICKINSON AND COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120183954-A1 | LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES | CD44, HLCS, GUSB | RXFP1 2048/4885ALDH1A1 407/4885LMNA 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.