Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
| ▸ | JUN | P05412 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357002 | 0.94 | KDM4E (0.48) | KDM4ETYRO3DYRK1BXDHALDH1A1 | |
| Hydrochloric Acid SCHEMBL4982874 | 0.92 | KDM4E (0.47) | KDM4ETYRO3DYRK1BXDHALDH1A1 | |
| SCHEMBL9239547 | 0.92 | KDM4E (0.47) | KDM4ETYRO3DYRK1BXDHALDH1A1 | |
| SCHEMBL30586390 | 0.74 | KDM4E (0.37) | KDM4ETYRO3DYRK1BXDHALDH1A1 | |
| SCHEMBL4480587 | 0.74 | KDM4E (0.33) | KDM4EALDH1A1PARP1GLAGAA | |
| SCHEMBL375954 | 0.74 | PDK2 (0.40) | KDM4EALDH1A1SMN1; SMN2PARP1GLA | |
| SCHEMBL4323514 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1SMN1; SMN2GLAGAA | |
| SCHEMBL276943 | 0.74 | KDM4E (0.35) | KDM4EXDHALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL25432823 | 0.72 | KDM4E (0.43) | KDM4ETYRO3DYRK1BALDH1A1SMN1; SMN2 | |
| SCHEMBL30850504 | 0.71 | EGFR (0.36) | KDM4ETYRO3XDHALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144632-A1 | NOVEL COMPOUNDS | PFIZER LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |