Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.55 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.55 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750712 | 0.86 | ANPEP (0.55) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL3235398 | 0.82 | ANPEP (0.52) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL800814 | 0.80 | — | — | |
| SCHEMBL14626876 | 0.79 | ANPEP (0.58) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL14560074 | 0.79 | SMN1; SMN2 (0.55) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL9868278 | 0.77 | ANPEP (0.56) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL2824432 | 0.77 | ANPEP (0.55) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL1567116 | 0.75 | — | — | |
| SCHEMBL667964 | 0.75 | — | — | |
| SCHEMBL13592115 | 0.74 | SMN1; SMN2 (0.50) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | claimed |
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |