Oxitriptan

Oxitriptan

SCHEMBL43242

NC(Cc1c[nH]c2ccc(O)cc12)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 6/20 1.00
HTR2C P28335 5/20 1.00
TSHR P16473 4/20 1.00
BLM P54132 4/20 1.00
LMNA P02545 4/20 1.00
HTR1A P08908 4/20 1.00
HTR2A P28223 4/20 1.00
HTR2B P41595 4/20 1.00
MAPT P10636 4/20 1.00
KDM4E B2RXH2 4/20 1.00
ALDH1A1 P00352 4/20 1.00
KMT2A Q03164 3/20 1.00
NFKB1 P19838 3/20 1.00
PMP22 Q01453 3/20 1.00
CYP3A4 P08684 3/20 1.00
HTR7 P34969 2/20 1.00
ADORA3 P0DMS8 1/20 1.00
ALOX15 P16050 1/20 1.00
SLC6A4 P31645 1/20 1.00
MTOR P42345 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxitriptan SCHEMBL21114383 1.00 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL29498813 1.00 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL43243 1.00 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL1421238 1.00 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL21114382 1.00 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL29366470 1.00 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL19871232 1.00 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL3033706 1.00 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL10448511 0.99 NPSR1 (0.97) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL990122 0.99 NPSR1 (0.97) NPSR1HTR2CTSHRBLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12735 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4746864-A1 C5 KETONE COMPOSITIONS AND RELATED METHODS FOR TREATING METABOLIC DYSFUNCTION Keto Innovations, LLC (US) 2026-05-27 EP claimed
CN-122056386-A Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-19 CN claimed
WO-2026099341-A1 BIOCONTAINMENT OF UNWANTED ENGINEERED CELLS USING NON-NATURAL AMINO ACIDS SNIPR BIOME APS (DK) 2026-05-15 WO claimed
CN-122030612-A Shear-resistant slow-release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-15 CN claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-12622857-B2 Skin lightening composition Bella Aurora Labs, S.A. (ES) 2026-05-12 US claimed
US-20260116915-A1 A Chemoselective Photochemical Bioconjugation Reaction and Methods of Use Thereof TRUSTEES BOSTON COLLEGE (US) 2026-04-30 US claimed
WO-2026090582-A1 COMPOSITIONS CONTAINING A NON-XANTHINE CNS STIMULANT OR NOOTROPIC AND BETA-HYDROXYBUTYRATE OR PRECURSOR FOR INCREASING NEUROLOGICAL AND PHYSIOLOGICAL PERFORMANCE AXCESS GLOBAL SCIENCES, LLC (US) 2026-04-30 WO claimed
US-12589152-B2 Composition for enhanced absorption of supplements The LIV Group Inc. (US) 2026-03-31 US claimed
US-4472387-A 5-HYDROXYTRYPTOPHAN OR ESTER, NITROGEN HETEROCYCLE PANMEDICA S.A. (FR) 1984-09-18 US claimed
EP-0106281-A2 Analgesia-effecting 5-hydroxytryptophan derivatives YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) 1984-04-25 EP claimed
EP-0085283-A1 Pyroglutamyl-tryptophan derivatives, process for their preparation and their therapeutic applications Società Italo-Britannica L. Manetti - H. Roberts & C. (IT) 1983-08-10 EP claimed
US-4326060-A 6-FORMYLPTERIN, P-AMINOBENZOYL AMINO ACID BAKER INSTRUMENTS CORPORATION (US) 1982-04-20 US claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-4283337-A Process for the purification of tryptophane and derivatives of tryptophane DEUTSCHE GOLD UND- SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-08-11 US claimed
US-4042329-A Method and device for detecting cholesterol BECTON, DICKINSON AND COMPANY (US) 1977-08-16 US claimed
US-3964871-A GLUCOSE OXIDASE, HORSERADISH PEROXIDASE BECTON, DICKINSON AND COMPANY (US) 1976-06-22 US claimed
US-3963572-A Fermentative process for the production of L-tryptophan and its derivatives AB BOFORS (SW) 1976-06-15 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed