Oxitriptan

Oxitriptan

SCHEMBL990122

NC(Cc1c[nH]c2ccc(O)cc12)C(=O)O.NC(Cc1c[nH]c2ccc(O)cc12)C(=O)O.NC(Cc1c[nH]c2ccc(O)cc12)C(=O)O.[Cr]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 6/20 0.97
HTR2C P28335 5/20 0.97
TSHR P16473 4/20 0.97
BLM P54132 4/20 0.97
LMNA P02545 4/20 0.97
HTR1A P08908 4/20 0.97
HTR2A P28223 4/20 0.97
HTR2B P41595 4/20 0.97
MAPT P10636 4/20 0.97
KDM4E B2RXH2 4/20 0.97
ALDH1A1 P00352 4/20 0.97
KMT2A Q03164 3/20 0.97
NFKB1 P19838 3/20 0.97
PMP22 Q01453 3/20 0.97
CYP3A4 P08684 3/20 0.97
HTR7 P34969 2/20 0.97
ADORA3 P0DMS8 1/20 0.97
ALOX15 P16050 1/20 0.97
SLC6A4 P31645 1/20 0.97
MTOR P42345 1/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxitriptan SCHEMBL4452810 1.00 NPSR1 (0.97) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL4452809 1.00 NPSR1 (0.97) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL990124 1.00 NPSR1 (0.97) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL3033706 0.99 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL1421238 0.99 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL19871232 0.99 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL29498813 0.99 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL21114382 0.99 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL21114383 0.99 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA
Oxitriptan SCHEMBL43242 0.99 NPSR1 (1.00) NPSR1HTR2CTSHRBLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4069206-B1 SOLID FORM FORMULATION COMPRISING CHROMIUM OR COPPER OR A VITAMIN, COMPOSITIONS AND USES THEREOF ALESCO SRL (IT) 2024-08-07 EP claimed
US-20230013586-A1 SOLID FORM FORMULATION COMPRISING CHROMIUM OR COPPER OR A VITAMIN, COMPOSITIONS AND USES THEREOF PHARMANUTRA S.P.A. (IT) 2023-01-19 US claimed
EP-4070801-A1 COMPOSITIONS OF INSULIN AND CHROMIUM FOR THE TREATMENT AND PREVENTION OF DIABETES, HYPOGLYCEMIA AND RELATED DISORDERS Nutrition 21, LLC (US) 2022-10-12 EP claimed
EP-4069206-A1 SOLID FORM FORMULATION COMPRISING CHROMIUM OR COPPER OR A VITAMIN, COMPOSITIONS AND USES THEREOF Alesco S.r.l. (IT) 2022-10-12 EP claimed
WO-2021111407-A1 SOLID FORM FORMULATION COMPRISING CHROMIUM OR COPPER OR A VITAMIN, COMPOSITIONS AND USES THEREOF ALESCO S.R.L. (IT) 2021-06-10 WO claimed
EP-3513790-A1 CHROMIUM COMPLEXES AS ENHANCERS OF BRAIN GLUCOSE TRANSPORTERS JDS Therapeutics, LLC (US) 2019-07-24 EP claimed
EP-2448412-B1 CHROMIUM COMPLEXES AS ENHANCERS OF BRAIN GLUCOSE TRANSPORTERS JDS THERAPEUTICS LLC (US) 2019-05-01 EP claimed
US-20150224140-A1 CHROMIUM COMPLEXES AS ENHANCERS OF BRAIN GLUCOSE TRANSPORTERS CAPITAL ONE, NATIONAL ASSOCIATION, AS AGENT 2015-08-13 US claimed
EP-2012770-A2 TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE Interhealth Nutraceuticals, Inc. (US) 2009-01-14 EP claimed
WO-2007121312-A9 TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE INTERHEALTH NUTRACEUTICALS INC (US) 2008-07-17 WO claimed
WO-2007121312-A2 TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE INTERHEALTH NUTRACEUTICALS, INC. (US) 2007-10-25 WO claimed
US-20250275982-A1 SOLID FORM FORMULATION COMPRISING CHROMIUM OR COPPER OR A VITAMIN, COMPOSITIONS AND USES THEREOF ALESCO S.R.L. (IT) 2025-09-04 US disclosed
EP-4069206-B1 SOLID FORM FORMULATION COMPRISING CHROMIUM OR COPPER OR A VITAMIN, COMPOSITIONS AND USES THEREOF ALESCO SRL (IT) 2024-08-07 EP disclosed
EP-4282281-A2 SOLID FORM FORMULATION COMPRISING CHROMIUM OR COPPER OR A VITAMIN, COMPOSITIONS AND USES THEREOF Alesco S.r.l. (IT) 2023-11-29 EP disclosed
US-20230013586-A1 SOLID FORM FORMULATION COMPRISING CHROMIUM OR COPPER OR A VITAMIN, COMPOSITIONS AND USES THEREOF PHARMANUTRA S.P.A. (IT) 2023-01-19 US disclosed
WO-2011002939-A1 CHROMIUM COMPLEXES AS ENHANCERS OF BRAIN GLUCOSE TRANSPORTERS NUTRITION 21, INC. (US) 2011-01-06 WO disclosed
US-20090092560-A1 TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE INTERHEALTH NUTRACEUTICALS, INC. (US) 2009-04-09 US disclosed
EP-2012770-A2 TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE Interhealth Nutraceuticals, Inc. (US) 2009-01-14 EP disclosed
WO-2007121312-A9 TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE INTERHEALTH NUTRACEUTICALS INC (US) 2008-07-17 WO disclosed
WO-2007121312-A2 TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE INTERHEALTH NUTRACEUTICALS, INC. (US) 2007-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150224140-A1 CHROMIUM COMPLEXES AS ENHANCERS OF BRAIN GLUCOSE TRANSPORTERS SLC2A3, SLC2A1, SLC2A2 NPSR1 1729/4885HTR2C 1176/4885TSHR 1279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.