Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6117825 | 0.88 | KDM4E (0.54) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL6819069 | 0.86 | MAPT (0.64) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8118521 | 0.84 | ALDH1A1 (0.65) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1239718 | 0.83 | ALDH1A1 (0.63) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL7165775 | 0.83 | MAPT (0.67) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL26816572 | 0.81 | ALDH1A1 (0.61) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL15434035 | 0.81 | ALDH1A1 (0.75) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL4223927 | 0.81 | KDM4E (0.75) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL7822457 | 0.81 | KDM4E (1.00) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL7822461 | 0.81 | KDM4E (1.00) | KDM4EMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147216-A1 | NEW PYRIDINE DERIVATIVES AS LEPTIN RECEPTOR MODULATOR MIMETICS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | claimed |
| WO-2009147216-A1 | NEW PYRIDINE DERIVATIVES AS LEPTIN RECEPTOR MODULATOR MIMETICS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |
| US-4140860-A | BACTERICIDES | STERLING DRUG INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4119668-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4085144-A | ANTIBACTERIAL | STERLING DRUG INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4022833-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1977-05-10 | — | — | US | disclosed |