SCHEMBL432536

SCHEMBL432536

O=C(O)C1C2CC(C1C(=O)O)C(C(=O)O)C2C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.57
TDP1 Q9NUW8 3/20 0.57
MAPK1 P28482 1/20 0.42
LMNA P02545 4/20 0.41
PMP22 Q01453 2/20 0.41
TSHR P16473 2/20 0.41
KDM4E B2RXH2 2/20 0.41
APEX1 P27695 1/20 0.41
GMNN O75496 1/20 0.41
TFPI2 P48307 1/20 0.41
TP53 P04637 1/20 0.41
NFKB1 P19838 1/20 0.41
THPO P40225 1/20 0.41
CYP2D6 P10635 2/20 0.40
BLM P54132 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
ALOX15 P16050 1/20 0.40
RAB9A P51151 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8978055 0.93 POLB (0.57) POLBTDP1MAPK1LMNAPMP22
SCHEMBL3425859 0.87 POLB (0.52) POLBTDP1MAPK1LMNAPMP22
SCHEMBL16249737 0.84 POLB (0.50) POLBTDP1MAPK1LMNAPMP22
SCHEMBL29426398 0.84 POLB (0.50) POLBTDP1MAPK1LMNAPMP22
SCHEMBL6321813 0.84 POLB (0.44) POLBTDP1MAPK1LMNAPMP22
SCHEMBL16361417 0.82 POLB (0.48) POLBTDP1MAPK1LMNAPMP22
SCHEMBL12763440 0.82 POLB (0.48) POLBTDP1MAPK1LMNAPMP22
SCHEMBL13216614 0.82 MAPK1 (0.55) POLBTDP1MAPK1LMNAPMP22
SCHEMBL3025318 0.82 MAPK1 (0.55) POLBTDP1MAPK1LMNAPMP22
SCHEMBL16249905 0.80 POLB (0.52) POLBTDP1MAPK1LMNAPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232017-B Compound, resin and preparation method and application thereof 华为技术有限公司 2024-06-18 CN claimed
CN-118047948-A Resin, preparation method thereof and resin composition 华为技术有限公司 2024-05-17 CN claimed
CN-117304037-A Diamine monomer, preparation method thereof, resin and application thereof 华为技术有限公司 2023-12-29 CN claimed
CN-115232017-A Compound, resin, and preparation method and application thereof 华为技术有限公司 2022-10-25 CN claimed
US-20220204693-A1 Polyamide-Imide Copolymer and Film Containing the Same MICROCOSM TECHNOLOGY CO., LTD. (TW) 2022-06-30 US claimed
US-20210364919-A1 PHOTOSENSITIVE RESIN COMPOSITION AND APPLICATION THEREOF MICROCOSM TECHNOLOGY CO., LTD. (TW) 2021-11-25 US claimed
US-20210109443-A1 PHOTOSENSITIVE POLYIMIDE RESIN COMPOSITION AND POLYIMIDE FILM THEREOF MICROCOSM TECHNOLOGY CO., LTD. (TW) 2021-04-15 US claimed
US-20210088903-A1 PHOTOSENSITIVE POLYIMIDE RESIN COMPOSITION AND POLYIMIDE FILM THEREOF MICROCOSM TECHNOLOGY CO., LTD. (TW) 2021-03-25 US claimed
US-20140171588-A1 COMPOSITION FOR FLEXIBLE SUBSTRATE AND FLEXIBLE SUBSTRATE FORMED FROM THE SAME CHI MEI CORPORATION (TW) 2014-06-19 US claimed
CN-101679633-B Resin composition for forming heat-cured film NISSAN CHEMICAL IND LTD 2012-09-19 CN claimed
US-7041766-B2 Colorless and transparent polyimidesilicone resin having thermosetting functional groups SHIN-ETSU CHEMICAL CO., LTD (JP) 2006-05-09 US claimed
EP-1518881-A2 Polymer modified by a polyether as adjuvant in leather manufacture Bayer Chemicals AG (DE) 2005-03-30 EP claimed
US-20050058619-A1 Polyether-modified polymers as leather auxiliaries LANXESS DEUTSCHLAND GMBH (DE) 2005-03-17 US claimed
JP-63057557-A None JP disclosed
JP-63057589-A None JP disclosed
JP-63057589-A None JP disclosed
JP-S6357589-A BICYCLO(2.2.1)HEPTANE-2,3,5,6-TETRACARBOXYLIC ACID DIANHYDRIDE AND PRODUCTION THEREOF DAINIPPON INK & CHEM INC 1988-03-12 JP disclosed
JP-S6357557-A BICYCLO(2.2.1)HEPTANE-2,3,5,6-TETRACARBOXYLIC ACID TETRAESTERS AND PRODUCTION THEREOF DAINIPPON INK & CHEM INC 1988-03-12 JP disclosed
JP-S6357657-A NOVEL HEAT-RESISTANT POLYVINYL CHLORIDE COMPOSITION DAINIPPON INK & CHEM INC 1988-03-12 JP disclosed
JP-S6357589-A BICYCLO(2.2.1)HEPTANE-2,3,5,6-TETRACARBOXYLIC ACID DIANHYDRIDE AND PRODUCTION THEREOF DAINIPPON INK & CHEM INC 1988-03-12 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050058619-A1 Polyether-modified polymers as leather auxiliaries PUF60, B2M, CBR3 POLB 1986/4885TDP1 4570/4885MAPK1 2758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.