Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432536 | 0.93 | POLB (0.57) | POLBTDP1LMNAPMP22TSHR | |
| SCHEMBL6561586 | 0.82 | POLB (0.42) | POLBTDP1LMNAPMP22TSHR | |
| SCHEMBL3425859 | 0.80 | POLB (0.52) | POLBTDP1LMNAPMP22TSHR | |
| SCHEMBL16249905 | 0.80 | POLB (0.52) | POLBTDP1LMNAPMP22TSHR | |
| SCHEMBL29488848 | 0.80 | PPM1B (0.52) | POLBTDP1CYP1A2CYP2C19MEN1 | |
| SCHEMBL12231001 | 0.79 | POLB (0.48) | POLBTDP1LMNAPMP22TSHR | |
| SCHEMBL20540759 | 0.78 | POLB (0.44) | POLBTDP1LMNAPMP22TSHR | |
| SCHEMBL20540760 | 0.78 | POLB (0.44) | POLBTDP1LMNAPMP22TSHR | |
| SCHEMBL20540937 | 0.78 | POLB (0.44) | POLBTDP1LMNAPMP22TSHR | |
| SCHEMBL20540761 | 0.78 | POLB (0.44) | POLBTDP1LMNAPMP22TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707572-A1 | IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME | BRACCO S.p.A. (IT) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001966-A1 | IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME | BRACCO S.P.A. (IT) | 1995-01-19 | — | — | WO | disclosed |