SCHEMBL432550

SCHEMBL432550

C=C(C[Si](OC)(OC)OC)C(=O)OCCC

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
THRB P10828 1/20 0.35
HCAR2 Q8TDS4 1/20 0.32
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.31
ESR1 P03372 1/20 0.30
CHRM1 P11229 1/20 0.30
SLC6A2 P23975 1/20 0.30
KDR P35968 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19548014 0.88 TSHR (0.31) TSHR
SCHEMBL6686188 0.84 TSHR (0.37) TSHRTHRBHCAR2GAASMN1; SMN2
SCHEMBL6685867 0.84 THRB (0.38) TSHRTHRBHCAR2GAASMN1; SMN2
Acrylic Acid SCHEMBL19547974 0.83 HCAR2 (0.33) HCAR2
SCHEMBL1819157 0.82 TSHR (0.36) TSHRTHRBHCAR2GAASMN1; SMN2
SCHEMBL1219576 0.81 TSHR (0.40) TSHRTHRBHCAR2GAASMN1; SMN2
SCHEMBL16535339 0.81 TSHR (0.35) TSHRTHRBHCAR2
SCHEMBL2461312 0.81 TSHR (0.42) TSHRTHRBHCAR2ALDH1A1LMNA
SCHEMBL10871257 0.81 TSHR (0.35) TSHRTHRBHCAR2
SCHEMBL10610103 0.79 TSHR (0.39) TSHRTHRBHCAR2GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250019578-A1 ACRYLIC COPOLYMER COMPOSITIONS FOR USE AS SEALANTS ROHM AND HAAS COMPANY 2025-01-16 US claimed
EP-4444770-A1 ACRYLIC COPOLYMER COMPOSITIONS FOR USE AS SEALANTS Rohm and Haas Company (US) 2024-10-16 EP claimed
CN-112533910-B Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2024-05-10 CN claimed
CN-110173895-B Water heater with sterilization function and manufacturing method 海信(广东)厨卫系统有限公司 2023-10-17 CN claimed
CN-116284615-A High-efficiency extraction method and application of choline phosphate functionalized nano hydrogel structure and exosomes 南开大学 2023-06-23 CN claimed
WO-2023107204-A1 ACRYLIC COPOLYMER COMPOSITIONS FOR USE AS SEALANTS ROHM AND HAAS COMPANY (US) 2023-06-15 WO claimed
CN-109906411-B Nanocomposites containing crystalline polyesters and silicones 卡博特公司 2022-12-27 CN claimed
CN-111944091-B Preparation method of semi-polymerized ionic liquid-filled super-smooth surface 中国科学院兰州化学物理研究所 2022-01-18 CN claimed
CN-113795929-A Photovoltaic module having a film layer comprising hydrophobically treated fumed silica 陶氏环球技术有限责任公司 2021-12-14 CN claimed
CN-113767128-A Photovoltaic module with film layer comprising hydrophilic fumed silica 陶氏环球技术有限责任公司 2021-12-07 CN claimed
EP-0714416-A1 FREE RADICAL POLYMERISATION PROCESS ZENECA LIMITED (GB) 1996-06-05 EP claimed
WO-1996013527-A1 FREE RADICAL POLYMERISATION PROCESS ZENECA LIMITED (GB) 1996-05-09 WO claimed
WO-1995027737-A1 FREE RADICAL POLYMERISATION PROCESS ZENECA LIMITED (GB) 1995-10-19 WO claimed
WO-1995004759-A1 FREE RADICAL POLYMERISATION PROCESS ZENECA LIMITED (GB) 1995-02-16 WO claimed
EP-0479856-B1 PRECIPITATION POLYMERIZATION OF VINYL LACTAM TERPOLYMERS ISP INVESTMENTS INC (US) 1995-02-15 EP claimed
EP-0601219-A1 Waterbased acrylic silane and polyurethane containing coating composition E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-06-15 EP claimed
US-5204404-A Automobile paints E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-04-20 US claimed
EP-0479856-A4 PRECIPITATION POLYMERIZATION OF VINYL LACTAM TERPOLYMERS 1992-12-30 EP claimed
EP-0479856-A1 PRECIPITATION POLYMERIZATION OF VINYL LACTAM TERPOLYMERS. ISP INVESTMENTS INC (US) 1992-04-15 EP claimed
WO-1991000302-A1 PRECIPITATION POLYMERIZATION OF VINYL LACTAM TERPOLYMERS GAF CHEMICALS CORPORATION (US) 1991-01-10 WO claimed