Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333359 | 0.85 | CYP2C19 (0.52) | SRCLMNAALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL28290228 | 0.85 | CYP2C19 (0.52) | SRCLMNAALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL7516063 | 0.84 | ESR1 (0.41) | ESR1ESR2SRCFOLH1CNR1 | |
| SCHEMBL22338178 | 0.84 | PTGFR (0.46) | CNR2ALDH1A1KDM4EPTGS1PTGS2 | |
| SCHEMBL7603654 | 0.83 | ESR1 (0.62) | ESR1ESR2LMNAHSD17B10ALDH1A1 | |
| SCHEMBL4328325 | 0.82 | CNR1 (0.49) | ESR1ESR2SRCFOLH1CNR1 | |
| SCHEMBL27904288 | 0.81 | TDP1 (0.56) | ESR1ESR2SRCFOLH1LMNA | |
| SCHEMBL15636794 | 0.81 | TDP1 (0.50) | LMNAHSD17B10ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL8379019 | 0.79 | TAAR1 (0.58) | ALDH1A1TDP1SMN1; SMN2HTR1ATHPO | |
| SCHEMBL8379013 | 0.79 | TAAR1 (0.58) | ALDH1A1TDP1SMN1; SMN2HTR1ATHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |