Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | PTGFR | P43088 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290228 | 1.00 | CYP2C19 (0.52) | CYP2C19SMN1; SMN2BCAT2PTGFRCYP2D6 | |
| SCHEMBL20773139 | 0.85 | CTSD (0.55) | SMN1; SMN2BCAT2NPC1RAB9AMEN1 | |
| SCHEMBL4325567 | 0.85 | ESR1 (0.44) | CYP2C19SMN1; SMN2CYP2D6SRCPOLB | |
| SCHEMBL640978 | 0.85 | MTNR1A (0.58) | CYP2C19SMN1; SMN2BCAT2PTGFRNPC1 | |
| SCHEMBL6209721 | 0.85 | BCAT2 (0.66) | CYP2C19SMN1; SMN2BCAT2PTGFRCYP2D6 | |
| SCHEMBL5435795 | 0.85 | MTNR1A (0.58) | CYP2C19SMN1; SMN2BCAT2PTGFRNPC1 | |
| SCHEMBL7509646 | 0.83 | CYP2C19 (0.47) | CYP2C19SMN1; SMN2BCAT2PTGFRCYP2D6 | |
| SCHEMBL22338178 | 0.83 | PTGFR (0.46) | PTGFRMAPK1ALDH1A1 | |
| SCHEMBL29182112 | 0.83 | NPC1 (0.67) | CYP2C19SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL23320094 | 0.82 | ALDH1A1 (0.49) | SMN1; SMN2MEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |