Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 13/20 | 0.68 |
| ▸ | SMO | Q99835 | 5/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375137 | 0.83 | NR3C1 (0.66) | NR3C1SMOPGR | |
| SCHEMBL524419 | 0.81 | NR3C1 (1.00) | NR3C1PGR | |
| SCHEMBL524418 | 0.81 | NR3C1 (1.00) | NR3C1PGR | |
| SCHEMBL9943289 | 0.78 | NR3C1 (0.52) | NR3C1SMOPGR | |
| SCHEMBL12805049 | 0.77 | NR3C1 (0.59) | NR3C1SMOPGR | |
| SCHEMBL3814256 | 0.76 | NR3C1 (0.52) | NR3C1SMOPGR | |
| SCHEMBL835455 | 0.74 | NR3C1 (0.67) | NR3C1PGR | |
| SCHEMBL835456 | 0.74 | NR3C1 (0.67) | NR3C1PGR | |
| SCHEMBL12805643 | 0.74 | NR3C1 (0.56) | NR3C1SMOPGR | |
| SCHEMBL9943272 | 0.73 | NR3C1 (0.57) | NR3C1SMOPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102169-A1 | INDAZOLYL ESTER AND AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | AstraZeneca AB (SE) | 2009-09-23 | — | — | EP | claimed |
| WO-2008076048-A1 | INDAZOLYL ESTER AND AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | claimed |