Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 11/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578172 | 0.95 | RORC (0.43) | RORCPPARGEPHX2CSNK1EDYRK1A | |
| Trifluoroacetic Acid SCHEMBL4325196 | 0.86 | RORC (0.43) | RORCPPARGDYRK1ACLK2CLK3 | |
| Trifluoroacetic Acid SCHEMBL4318631 | 0.84 | ATM (0.45) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL4325301 | 0.83 | CNR2 (0.51) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL4329769 | 0.82 | ATM (0.44) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL4341502 | 0.81 | CNR2 (0.48) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL4333038 | 0.81 | KMT2A (0.48) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL13578193 | 0.81 | PPARG (0.44) | RORCPPARGEPHX2 | |
| Trifluoroacetic Acid SCHEMBL4322823 | 0.80 | MAPK1 (0.46) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL4333549 | 0.78 | ATM (0.42) | CASP3SENP8SENP7SENP6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | CASP3 3788/4885SENP8 4342/4885SENP7 4168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.