Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | ADH4 | P08319 | 1/20 | 0.40 |
| ▸ | ADH7 | P40394 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15004595 | 0.92 | TSHR (0.54) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL555018 | 0.91 | TSHR (0.46) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Hydrochloric Acid SCHEMBL6898636 | 0.90 | TSHR (0.52) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL15360400 | 0.88 | TSHR (0.48) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL272669 | 0.85 | TSHR (0.50) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL27999229 | 0.83 | TSHR (0.46) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL15360341 | 0.83 | TSHR (0.46) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL614388 | 0.81 | TSHR (0.44) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL28975742 | 0.80 | TSHR (0.39) | TSHRALDH1A1CYP1A2CYP2C19CA1 | |
| Methoxymethane SCHEMBL2150575 | 0.79 | TSHR (0.77) | TSHRALDH1A1S1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7575655-B2 | improving the adhesion of silicone rubber to a substrate, comprising applying a primer to form a uniform film coverings, drying and curing the composite; comprising organosilane compounds as couplers to form a strong bond between two parts | WACKER CHEMIE AG (DE) | 2009-08-18 | — | — | US | disclosed |
| US-20060207723-A1 | Primer for heat-curable silicone elastomers | WACKER CHEMIE AG (DE) | 2006-09-21 | — | — | US | disclosed |